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Home - Products - Metabolic Enzyme/Protease - Dehydrogenase - CVT-11127

CVT-11127

CAS No. 1018674-83-3

CVT-11127( —— )

Catalog No. M23225 CAS No. 1018674-83-3

CVT-11127 is an StearoylCoA Desaturase-1 (SCD1) inhibitor.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    CVT-11127
  • Note
    Research use only, not for human use.
  • Brief Description
    CVT-11127 is an StearoylCoA Desaturase-1 (SCD1) inhibitor.
  • Description
    CVT-11127 is an StearoylCoA Desaturase-1 (SCD1) inhibitor.
  • In Vitro
    CVT-11127 (1 μM, 48 h) shows antiproliferation activity in H460 cells.CVT-11127 (1 μM, 48 h) decreases the the population of cells in S-phase by 75%.CVT-11127 (1 μM, 48 h) induces apoposis in H460 cells.CVT-11127 (1, 2 μM) inhibitors the SCD (stearoylCoA desaturase) activity in H460 cells. Cell Proliferation Assay Cell Line:H460 cells Concentration:1 μM Incubation Time:48 h Result:Showed antiproliferation activity.Cell Cycle Analysis Cell Line:H460 cells Concentration:1 μM Incubation Time:48 h Result:Decreased the the population of cells in S-phase by 75%.Apoptosis Analysis Cell Line:H460 cells Concentration:1 μM Incubation Time:24 h Result:Induced apoposis H460 cells.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Metabolic Enzyme/Protease
  • Target
    Dehydrogenase
  • Recptor
    SCD1
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1018674-83-3
  • Formula Weight
    512.39
  • Molecular Formula
    C25H23Cl2N5O3
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:5 mM
  • SMILES
    CC(=O)NCCN1C2=C(C=CC(=N2)NCC3=CC(=C(C=C3)Cl)Cl)N=C(C1=O)C4=CC=C(C=C4)OC
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

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