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Teriflunomide impurity 3
CAS No. 1011244-72-6
Teriflunomide impurity 3( 4-Amino-N-(4-trifluoromethylphenyl)benzamide )
Catalog No. M23218 CAS No. 1011244-72-6
Teriflunomide impurity 3 is a selective COX-1 inhibitor(IC50 of 30 μM). It is less active against COX-2 (IC50>100 μM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 29 | In Stock |
|
| 10MG | 41 | In Stock |
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| 25MG | 79 | In Stock |
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| 50MG | 126 | In Stock |
|
| 100MG | 207 | In Stock |
|
| 200MG | 296 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameTeriflunomide impurity 3
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NoteResearch use only, not for human use.
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Brief DescriptionTeriflunomide impurity 3 is a selective COX-1 inhibitor(IC50 of 30 μM). It is less active against COX-2 (IC50>100 μM).
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DescriptionTeriflunomide impurity 3 is a selective COX-1 inhibitor(IC50 of 30 μM). It is less active against COX-2 (IC50>100 μM).
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In VitroTeriflunomide impurity 3 (4-Amino-N-(4-trifluoromethylphenyl)benzamide; compound 11q) is an amide-bond-reversed compound bearing trifluoromethyl and amino substituents showed potent COX-1-selective inhibitory activity.
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In Vivo——
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Synonyms4-Amino-N-(4-trifluoromethylphenyl)benzamide
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PathwayChromatin/Epigenetic
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TargetCOX
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RecptorCOX-1|COX-2
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Research Area——
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Indication——
Chemical Information
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CAS Number1011244-72-6
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Formula Weight280.25
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Molecular FormulaC14H11F3N2O
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Purity>98% (HPLC)
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SolubilityDMSO:250 mg/mL (892.06 mM; Need ultrasonic)
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SMILESO=C(NC1=CC=C(C(F)(F)F)C=C1)C2=CC=C(N)C=C2
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Hiroki Kakuta, et al. Cyclooxygenase-1-selective inhibitors are attractive candidates for analgesics that do not cause gastric damage. design and in vitro/in vivo evaluation of a benzamide-type cyclooxygenase-1 selective inhibitor. J Med Chem. 2008 Apr 24;51(8):2400-11.
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