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MitoBloCK-11?(MB-11)

CAS No. 413606-16-3

MitoBloCK-11?(MB-11)( —— )

Catalog No. M22985 CAS No. 413606-16-3

MitoBloCK-11 (MB-11) is a s mall molecule inhibitor of mitochondrial protein import possibly acts through transport protein Seo1, but not Tom70 or Tom20; inhibits precursor proteins that contain hydrophobic segments, confers growth in media lacking uracil in a specific manner and affects zebrafish development.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    MitoBloCK-11?(MB-11)
  • Note
    Research use only, not for human use.
  • Brief Description
    MitoBloCK-11 (MB-11) is a s mall molecule inhibitor of mitochondrial protein import possibly acts through transport protein Seo1, but not Tom70 or Tom20; inhibits precursor proteins that contain hydrophobic segments, confers growth in media lacking uracil in a specific manner and affects zebrafish development.
  • Description
    MitoBloCK-11 (MB-11) is a s mall molecule inhibitor of mitochondrial protein import possibly acts through transport protein Seo1, but not Tom70 or Tom20; inhibits precursor proteins that contain hydrophobic segments, confers growth in media lacking uracil in a specific manner and affects zebrafish development.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    mitochondrial protein import
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    413606-16-3
  • Formula Weight
    434.3
  • Molecular Formula
    C17H12BrN3O4S?
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 125 mg/mL (287.85 mM)
  • SMILES
    O=C(NN=CC1=CC=C([N+]([O-])=O)S1)COC2=C3C=CC=CC3=C(Br)C=C2
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Conti, M. (2018). Small Molecule Probes of Mitochondrial Translocases Elucidate PINK1 Trafficking in PINK1/Parkin Regulated Mitophagy. UCLA. 2. Miyata N, et al. J Biol Chem. 2017 Mar 31;292(13):5429-5442. View Related Products by Target Other Target
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