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MitoBloCK-11?(MB-11)
CAS No. 413606-16-3
MitoBloCK-11?(MB-11)( —— )
Catalog No. M22985 CAS No. 413606-16-3
MitoBloCK-11 (MB-11) is a s mall molecule inhibitor of mitochondrial protein import possibly acts through transport protein Seo1, but not Tom70 or Tom20; inhibits precursor proteins that contain hydrophobic segments, confers growth in media lacking uracil in a specific manner and affects zebrafish development.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 114 | In Stock |
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| 5MG | 98 | In Stock |
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| 10MG | 151 | In Stock |
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| 25MG | 250 | In Stock |
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| 50MG | 345 | In Stock |
|
| 100MG | 463 | In Stock |
|
| 200MG | 626 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameMitoBloCK-11?(MB-11)
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NoteResearch use only, not for human use.
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Brief DescriptionMitoBloCK-11 (MB-11) is a s mall molecule inhibitor of mitochondrial protein import possibly acts through transport protein Seo1, but not Tom70 or Tom20; inhibits precursor proteins that contain hydrophobic segments, confers growth in media lacking uracil in a specific manner and affects zebrafish development.
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DescriptionMitoBloCK-11 (MB-11) is a s mall molecule inhibitor of mitochondrial protein import possibly acts through transport protein Seo1, but not Tom70 or Tom20; inhibits precursor proteins that contain hydrophobic segments, confers growth in media lacking uracil in a specific manner and affects zebrafish development.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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Recptormitochondrial protein import
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Research Area——
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Indication——
Chemical Information
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CAS Number413606-16-3
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Formula Weight434.3
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Molecular FormulaC17H12BrN3O4S?
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 125 mg/mL (287.85 mM)
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SMILESO=C(NN=CC1=CC=C([N+]([O-])=O)S1)COC2=C3C=CC=CC3=C(Br)C=C2
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Conti, M. (2018). Small Molecule Probes of Mitochondrial Translocases Elucidate PINK1 Trafficking in PINK1/Parkin Regulated Mitophagy. UCLA. 2. Miyata N, et al. J Biol Chem. 2017 Mar 31;292(13):5429-5442. View Related Products by Target Other Target
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