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Levothyroxine sodium
CAS No. 55-03-8
Levothyroxine sodium( L-T4 sodium,L-Thyroxine sodium,LT4 sodium )
Catalog No. M22952 CAS No. 55-03-8
Levothyroxine, the major hormone derived from the thyroid gland, is the agonist of Thyroid hormone receptor alpha and beta.evothyroxine (L-T(4))can upregulate the expression of P-gp mRNA and protein in LS180 cells, but only L-T(4) and L-T(3) can produce the same effect in Caco-2 cells, which are relatively lacking in PXR.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 49 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | 42 | In Stock |
|
| 1G | 56 | In Stock |
|
Biological Information
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Product NameLevothyroxine sodium
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NoteResearch use only, not for human use.
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Brief DescriptionLevothyroxine, the major hormone derived from the thyroid gland, is the agonist of Thyroid hormone receptor alpha and beta.evothyroxine (L-T(4))can upregulate the expression of P-gp mRNA and protein in LS180 cells, but only L-T(4) and L-T(3) can produce the same effect in Caco-2 cells, which are relatively lacking in PXR.
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DescriptionLevothyroxine, the major hormone derived from the thyroid gland, is the agonist of Thyroid hormone receptor alpha and beta.evothyroxine (L-T(4))can upregulate the expression of P-gp mRNA and protein in LS180 cells, but only L-T(4) and L-T(3) can produce the same effect in Caco-2 cells, which are relatively lacking in PXR.
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In Vitro——
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In Vivo——
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SynonymsL-T4 sodium,L-Thyroxine sodium,LT4 sodium
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PathwayOthers
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TargetOther Targets
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RecptorThyroid Hormone
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Research AreaEndocrine system
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IndicationHypothyroidism
Chemical Information
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CAS Number55-03-8
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Formula Weight798.85
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Molecular FormulaC15H10I4NO4.Na
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Purity>98% (HPLC)
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SolubilityDMSO:100 mg/ml (125.18 mM)
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SMILESN[C@@H](CC1=CC(I)=C(OC2=CC(I)=C(O)C(I)=C2)C(I)=C1)C(O[Na])=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Mitin T, et al. Drug Metab Dispos. 2004, 32(8):779-82.
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