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IGS-1.76
CAS No. 313480-47-6
IGS-1.76( —— )
Catalog No. M22886 CAS No. 313480-47-6
IGS-1.76 shows a significantly increased affinity for hNCS-1 and is able to modulate the hNCS-1/Ric8a interaction efficiently.IGS-1.76 efficiently inhibits the human NCS-1/Ric8a complex.IGS-1.76, which efficiently inhibits the human NCS-1/Ric8a complex with improved binding potency.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 224 | In Stock |
|
| 10MG | 374 | In Stock |
|
| 25MG | 623 | In Stock |
|
| 50MG | 887 | In Stock |
|
| 100MG | 1197 | In Stock |
|
| 500MG | 2394 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameIGS-1.76
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NoteResearch use only, not for human use.
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Brief DescriptionIGS-1.76 shows a significantly increased affinity for hNCS-1 and is able to modulate the hNCS-1/Ric8a interaction efficiently.IGS-1.76 efficiently inhibits the human NCS-1/Ric8a complex.IGS-1.76, which efficiently inhibits the human NCS-1/Ric8a complex with improved binding potency.
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DescriptionIGS-1.76 shows a significantly increased affinity for hNCS-1 and is able to modulate the hNCS-1/Ric8a interaction efficiently.IGS-1.76 efficiently inhibits the human NCS-1/Ric8a complex.IGS-1.76, which efficiently inhibits the human NCS-1/Ric8a complex with improved binding potency.
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In VitroIGS-1.76 is a Drosophila NCS-1/IGS-1.76 complex inhibitor.
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorNCS-1/Ric8a
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Research Area——
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Indication——
Chemical Information
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CAS Number313480-47-6
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Formula Weight358.5
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Molecular FormulaC22H18N2OS
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 250 mg/mL (697.43 mM)
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SMILESO=C(CC(c1ccccc1)c2ccccc2)Nc3nc4ccccc4s3
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Carlos Roca, et al. Deciphering the Inhibition of the Neuronal Calcium Sensor 1 and the Guanine Exchange Factor Ric8a with a Small Phenothiazine Molecule for the Rational Generation of Therapeutic Synapse Function Regulators. J Med Chem. 2018 Jul 26;61(14):5910-5921.
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