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I-49 free base
CAS No. ——
I-49 free base( Pyrido[4,3-d]pyrimidin-7(6H)-one, 2-methyl-4-[[(1R)-1-[2-methyl-3-(trifluoromethyl)phenyl]ethyl]amino]-6-(tetrahydro-2H-pyran-4-yl)- )
Catalog No. M22764 CAS No. ——
I-49 is a novel benzylamino substituted pyridopyrimidinone as SOS1 inhibitor.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 357 | In Stock |
|
| 10MG | 597 | In Stock |
|
| 25MG | 882 | In Stock |
|
| 50MG | Get Quote | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
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Biological Information
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Product NameI-49 free base
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NoteResearch use only, not for human use.
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Brief DescriptionI-49 is a novel benzylamino substituted pyridopyrimidinone as SOS1 inhibitor.
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DescriptionI-49 is a novel benzylamino substituted pyridopyrimidinone as SOS1 inhibitor.
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In Vitro——
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In Vivo——
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SynonymsPyrido[4,3-d]pyrimidin-7(6H)-one, 2-methyl-4-[[(1R)-1-[2-methyl-3-(trifluoromethyl)phenyl]ethyl]amino]-6-(tetrahydro-2H-pyran-4-yl)-
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PathwayMAPK/ERK Signaling
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TargetRaf
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RecptorSOS1
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Research Area——
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Indication——
Chemical Information
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CAS Number——
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Formula Weight482.92
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Molecular FormulaC23H26ClF3N4O2
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Purity>98% (HPLC)
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Solubility——
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SMILESCl.C[C@@H](Nc1nc(C)nc2cc(=O)n(cc12)C1CCOCC1)c1cccc(c1C)C(F)(F)F
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.RAMHARTER JUERGEN,et al.Novel benzylamino substituted pyridopyrimidinone and derivative as SOS1 inhibitor.TW 201938557 A
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