Duvoglustat hydrochloride
CAS No. 73285-50-4
Duvoglustat hydrochloride( AT2220,1-Deoxynojirimycin,Moranoline )
Catalog No. M22641 CAS No. 73285-50-4
Duvoglustat is a potent and selective inhibitor of alpha-glucosidase, most commonly found in mulberry leaves. Duvoglustat is used to suppress the elevation of postprandial hyperglycemia.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 28 | In Stock |
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| 10MG | 31 | In Stock |
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| 25MG | 52 | In Stock |
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| 50MG | 73 | In Stock |
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| 100MG | 110 | In Stock |
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| 200MG | 161 | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameDuvoglustat hydrochloride
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NoteResearch use only, not for human use.
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Brief DescriptionDuvoglustat is a potent and selective inhibitor of alpha-glucosidase, most commonly found in mulberry leaves. Duvoglustat is used to suppress the elevation of postprandial hyperglycemia.
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DescriptionDuvoglustat is a potent and selective inhibitor of alpha-glucosidase, most commonly found in mulberry leaves. Duvoglustat is used to suppress the elevation of postprandial hyperglycemia.
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In Vitro——
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In Vivo1-Deoxynojirimycin hydrochloride (Duvoglustat hydrochloride) (20-80 mg/kg; i.v.; daily for four weeks) shows anti-obesity effect .1-Deoxynojirimycin hydrochloride significantly improves insulin sensitivity via activating insulin signaling PI3K/AKT pathway in skeletal muscle of db/db mice. Animal Model:db/db mice Dosage:20, 40, 80 mg/kg Administration:Intravenously; daily for four weeks Result:Significantly reduced body weight, blood glucose and serum insulin levels; Improved glucose tolerance and insulin tolerance.
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SynonymsAT2220,1-Deoxynojirimycin,Moranoline
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PathwayCytoskeleton/Cell Adhesion Molecules
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TargetGlucokinase
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Recptorα-glucosidase
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Research Area——
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Indication——
Chemical Information
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CAS Number73285-50-4
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Formula Weight199.63
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Molecular FormulaC6H14ClNO4
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Purity>98% (HPLC)
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SolubilityIn Vitro:?H2O : 250 mg/mL (1252.32 mM)
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SMILESCl.OC[C@H]1NC[C@H](O)[C@@H](O)[C@@H]1O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Chen G H , Tong J J , Wang F , et al. Chronic adjunction of 1-deoxynojirimycin protects from age-related behavioral and biochemical changes in the SAMP8 mice[J]. Age, 2015, 37(5):102.
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