Duvoglustat hydrochloride

CAS No. 73285-50-4

Duvoglustat hydrochloride( AT2220,1-Deoxynojirimycin,Moranoline )

Catalog No. M22641 CAS No. 73285-50-4

Duvoglustat is a potent and selective inhibitor of alpha-glucosidase, most commonly found in mulberry leaves. Duvoglustat is used to suppress the elevation of postprandial hyperglycemia.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 28 In Stock
10MG 31 In Stock
25MG 52 In Stock
50MG 73 In Stock
100MG 110 In Stock
200MG 161 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Duvoglustat hydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    Duvoglustat is a potent and selective inhibitor of alpha-glucosidase, most commonly found in mulberry leaves. Duvoglustat is used to suppress the elevation of postprandial hyperglycemia.
  • Description
    Duvoglustat is a potent and selective inhibitor of alpha-glucosidase, most commonly found in mulberry leaves. Duvoglustat is used to suppress the elevation of postprandial hyperglycemia.
  • In Vitro
    ——
  • In Vivo
    1-Deoxynojirimycin hydrochloride (Duvoglustat hydrochloride) (20-80 mg/kg; i.v.; daily for four weeks) shows anti-obesity effect .1-Deoxynojirimycin hydrochloride significantly improves insulin sensitivity via activating insulin signaling PI3K/AKT pathway in skeletal muscle of db/db mice. Animal Model:db/db mice Dosage:20, 40, 80 mg/kg Administration:Intravenously; daily for four weeks Result:Significantly reduced body weight, blood glucose and serum insulin levels; Improved glucose tolerance and insulin tolerance.
  • Synonyms
    AT2220,1-Deoxynojirimycin,Moranoline
  • Pathway
    Cytoskeleton/Cell Adhesion Molecules
  • Target
    Glucokinase
  • Recptor
    α-glucosidase
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    73285-50-4
  • Formula Weight
    199.63
  • Molecular Formula
    C6H14ClNO4
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?H2O : 250 mg/mL (1252.32 mM)
  • SMILES
    Cl.OC[C@H]1NC[C@H](O)[C@@H](O)[C@@H]1O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Chen G H , Tong J J , Wang F , et al. Chronic adjunction of 1-deoxynojirimycin protects from age-related behavioral and biochemical changes in the SAMP8 mice[J]. Age, 2015, 37(5):102.
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