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GRP-60367

CAS No. 1309241-34-6

GRP-60367( —— )

Catalog No. M22631 CAS No. 1309241-34-6

GRP-60367 is the first small molecule rabies virus (RABV) entry inhibitor, which has nanomolar effect on some RABV strains.Grp-60367 inhibits the entry of a subset of the RABV strain.Grp-60367 showed the specificity and effective anti-RABV activity of the scaffold. In the dose-response analysis, the EC50s range from 2 to 52 nM in different host cell lines.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 183 In Stock
5MG 169 In Stock
10MG 258 In Stock
25MG 426 In Stock
50MG 586 In Stock
100MG 792 In Stock
200MG 1051 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
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Biological Information

  • Product Name
    GRP-60367
  • Note
    Research use only, not for human use.
  • Brief Description
    GRP-60367 is the first small molecule rabies virus (RABV) entry inhibitor, which has nanomolar effect on some RABV strains.Grp-60367 inhibits the entry of a subset of the RABV strain.Grp-60367 showed the specificity and effective anti-RABV activity of the scaffold. In the dose-response analysis, the EC50s range from 2 to 52 nM in different host cell lines.
  • Description
    GRP-60367 is the first small molecule rabies virus (RABV) entry inhibitor, which has nanomolar effect on some RABV strains.Grp-60367 inhibits the entry of a subset of the RABV strain.Grp-60367 showed the specificity and effective anti-RABV activity of the scaffold. In the dose-response analysis, the EC50s range from 2 to 52 nM in different host cell lines.
  • In Vitro
    GRP-60367 inhibits entry of a subset of RABV strains. GRP-60367 shows specific and potent anti-RABV activity of the scaffold, returning in dose-response assays EC50s ranging from 2 to 52?nM on different host cell lines.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    RABV
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1309241-34-6
  • Formula Weight
    353.46
  • Molecular Formula
    C21H27N3O2
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    Cc1ccc(C)c(OCCNC2CCN(CC2)C(=O)c2ccncc2)c1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Pont V D , Wirblich C , Yoon J J , et al. Identification and Characterization of a Small-Molecule Rabies Virus Entry Inhibitor[J]. Journal of Virology, 2020, 94(13).
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