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GRP-60367
CAS No. 1309241-34-6
GRP-60367( —— )
Catalog No. M22631 CAS No. 1309241-34-6
GRP-60367 is the first small molecule rabies virus (RABV) entry inhibitor, which has nanomolar effect on some RABV strains.Grp-60367 inhibits the entry of a subset of the RABV strain.Grp-60367 showed the specificity and effective anti-RABV activity of the scaffold. In the dose-response analysis, the EC50s range from 2 to 52 nM in different host cell lines.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 183 | In Stock |
|
| 5MG | 169 | In Stock |
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| 10MG | 258 | In Stock |
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| 25MG | 426 | In Stock |
|
| 50MG | 586 | In Stock |
|
| 100MG | 792 | In Stock |
|
| 200MG | 1051 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameGRP-60367
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NoteResearch use only, not for human use.
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Brief DescriptionGRP-60367 is the first small molecule rabies virus (RABV) entry inhibitor, which has nanomolar effect on some RABV strains.Grp-60367 inhibits the entry of a subset of the RABV strain.Grp-60367 showed the specificity and effective anti-RABV activity of the scaffold. In the dose-response analysis, the EC50s range from 2 to 52 nM in different host cell lines.
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DescriptionGRP-60367 is the first small molecule rabies virus (RABV) entry inhibitor, which has nanomolar effect on some RABV strains.Grp-60367 inhibits the entry of a subset of the RABV strain.Grp-60367 showed the specificity and effective anti-RABV activity of the scaffold. In the dose-response analysis, the EC50s range from 2 to 52 nM in different host cell lines.
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In VitroGRP-60367 inhibits entry of a subset of RABV strains. GRP-60367 shows specific and potent anti-RABV activity of the scaffold, returning in dose-response assays EC50s ranging from 2 to 52?nM on different host cell lines.
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorRABV
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Research Area——
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Indication——
Chemical Information
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CAS Number1309241-34-6
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Formula Weight353.46
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Molecular FormulaC21H27N3O2
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Purity>98% (HPLC)
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Solubility——
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SMILESCc1ccc(C)c(OCCNC2CCN(CC2)C(=O)c2ccncc2)c1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Pont V D , Wirblich C , Yoon J J , et al. Identification and Characterization of a Small-Molecule Rabies Virus Entry Inhibitor[J]. Journal of Virology, 2020, 94(13).
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