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Home - Products - Immunology/Inflammation - NOS - S-Nitroso-N-acetyl-DL-penicillamine

S-Nitroso-N-acetyl-DL-penicillamine

CAS No. 67776-06-1

S-Nitroso-N-acetyl-DL-penicillamine( SNAP )

Catalog No. M22495 CAS No. 67776-06-1

S-Nitroso-N-acetyl-DL-penicillamine acts as a stable inhibitor of platelet aggregation, is a nitric oxide donor and . S-Nitroso-N-acetyl-DL-penicillamine (10 mM; 8 hours) after 6 hours under normoxic conditions by releasing nitric oxide (NO)induces toxicity of about 80% .

Purity : >98% (HPLC)

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Biological Information

  • Product Name
    S-Nitroso-N-acetyl-DL-penicillamine
  • Note
    Research use only, not for human use.
  • Brief Description
    S-Nitroso-N-acetyl-DL-penicillamine acts as a stable inhibitor of platelet aggregation, is a nitric oxide donor and . S-Nitroso-N-acetyl-DL-penicillamine (10 mM; 8 hours) after 6 hours under normoxic conditions by releasing nitric oxide (NO)induces toxicity of about 80% .
  • Description
    S-Nitroso-N-acetyl-DL-penicillamine acts as a stable inhibitor of platelet aggregation, is a nitric oxide donor and . S-Nitroso-N-acetyl-DL-penicillamine (10 mM; 8 hours) after 6 hours under normoxic conditions by releasing nitric oxide (NO)induces toxicity of about 80% . S-Nitroso-N-acetyl-DL-penicillamine has a half-time about 6 hours in in isolated rat ventricular myocytes. S-Nitroso-N-acetyl-DL-penicillamine (100 μM; 30 minutes) causes sustained decrease in the basal pHi in isolated rat ventricular myocytes.
  • In Vitro
    Cell Viability Assay Cell Line:Rat liver sinusoidal endothelial cells Concentration:2 mM, 5 mM, 10 mM Incubation Time:2 hours, 4 hours, 6 hours, 8 hours Result:Exhibited cytotoxicity against cultivated endothelial cells.
  • In Vivo
    ——
  • Synonyms
    SNAP
  • Pathway
    Immunology/Inflammation
  • Target
    NOS
  • Recptor
    NO Synthase
  • Research Area
    Others
  • Indication
    Anesthesia

Chemical Information

  • CAS Number
    67776-06-1
  • Formula Weight
    220.25
  • Molecular Formula
    C7H12N2O4S
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:250 mg/mL (1135.07 mM; Need ultrasonic)
  • SMILES
    CC(=O)NC(C(O)=O)C(C)(C)SN=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. E. Salas, et al. Comparative pharmacology of analogues of S-nitroso-N-acetyl-DL-penicillamine on human platelets. Br J Pharmacol. 1994 Aug;112(4):1071-6.
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