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DSP-4 hydrochloride

CAS No. 40616-75-9

DSP-4 hydrochloride( Neurotoxin DSP 4 (hydrochloride) )

Catalog No. M22486 CAS No. 40616-75-9

DSP-4 hydrochloride (Neurotoxin DSP 4 hydrochloride) can be used for the temporary selective degradation of the central and peripheral noradrenergic neurons, mainly those from the locus coeruleus (LC).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 48 In Stock
5MG 43 In Stock
10MG 61 In Stock
50MG 151 In Stock
100MG 233 In Stock
200MG 348 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
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Biological Information

  • Product Name
    DSP-4 hydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    DSP-4 hydrochloride (Neurotoxin DSP 4 hydrochloride) can be used for the temporary selective degradation of the central and peripheral noradrenergic neurons, mainly those from the locus coeruleus (LC).
  • Description
    DSP-4 hydrochloride (Neurotoxin DSP 4 hydrochloride) can be used for the temporary selective degradation of the central and peripheral noradrenergic neurons, mainly those from the locus coeruleus (LC). is a highly selective neurotoxin and readily passes the blood-brain barrier with neurotoxic effects on noradrenergic neurons of adult and developing rats.
  • In Vitro
    ——
  • In Vivo
    Animal Model:rats Dosage:50 mg/kg Administration:intraperitoneal , single Result:Not visualized large projection neurons and the fibers of the LC.
  • Synonyms
    Neurotoxin DSP 4 (hydrochloride)
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    40616-75-9
  • Formula Weight
    313.06
  • Molecular Formula
    C11H16BrCl2N
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:125 mg/mL (399.28 mM; Need ultrasonic)
  • SMILES
    Cl.CCN(CCCl)Cc1ccccc1Br
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Hormigo S, et al. The selective neurotoxin DSP-4 impairs the noradrenergic projections from the locus coeruleus to the inferior colliculus in rats. Front Neural Circuits. 2012 Jun 28;6:41.
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