Cart
sales@molnova.com
Bupranolol
CAS No. 14556-46-8
Bupranolol( —— )
Catalog No. M22226 CAS No. 14556-46-8
Bupranolol is an antagonist of β2-adrenergic receptor,and has been used for angina pectoris, hypertension, glaucoma, cardiac arrhythmia and as an antithrombotic.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 98 | In Stock |
|
| 5MG | 107 | In Stock |
|
| 10MG | 162 | In Stock |
|
| 25MG | 326 | In Stock |
|
| 50MG | 455 | In Stock |
|
| 100MG | 603 | In Stock |
|
| 200MG | 812 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameBupranolol
-
NoteResearch use only, not for human use.
-
Brief DescriptionBupranolol is an antagonist of β2-adrenergic receptor,and has been used for angina pectoris, hypertension, glaucoma, cardiac arrhythmia and as an antithrombotic.
-
DescriptionBupranolol is an antagonist of β2-adrenergic receptor，and has been used for angina pectoris, hypertension, glaucoma, cardiac arrhythmia and as an antithrombotic.
-
In VitroBupranolol (1~3 μM) shifts isoprenaline-induced relaxation in the presence of 30 μM propranolol. Bupranolol acts as a competitive antagonist of isoprenaline-induced relaxation in the presence of 300 nM propranolol, with a pA2 value of 5.90. Bupranolol antagonizes β1- and β2-ARs with pA2 values of ≈9.0, and also antagonizes β3-AR with a pA2 value of 6.0.
-
In Vivo——
-
Synonyms——
-
PathwayAngiogenesis
-
TargetAdrenergic Receptor
-
Recptorβ2-adrenergic receptor
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number14556-46-8
-
Formula Weight271.78
-
Molecular FormulaC14H22ClNO2
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 50 mg/mL (183.97 mM)
-
SMILESOC(COC1=C(Cl)C=CC(C)=C1)CNC(C)(C)C
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Malinowska B , Kie?-Kononowicz K , Flau K , et al. Atypical cardiostimulant β-adrenoceptor in the rat heart: stereoselective antagonism by bupranolol but lack of effect by some bupranolol analogues[J]. 2003, 139(8):1548-1554.
molnova catalog
related products
-
Tolazoline
Tolazoline, a non-selective competitive α-adrenergic receptor antagonist, is used as a vasodilator to treat spasms of peripheral blood vessels.
-
Bunazosin Hydrochlor...
Bunazosin Hydrochloride is an alpha(1)-adrenoceptor antagonist used as a systemic antihypertensive and an ocular hypotensive drug.
-
Citrulline
Citrulline is an α-amino acid.
