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IM156
CAS No. 1422365-93-2
IM156( —— )
Catalog No. M22096 CAS No. 1422365-93-2
IM156 is an orally bioavailable mitochondrial oxidative phosphorylation (OxPhos) inhibitor, with potential antineoplastic activity.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 80 | In Stock |
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| 5MG | 72 | In Stock |
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| 10MG | 116 | In Stock |
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| 25MG | 188 | In Stock |
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| 50MG | 346 | In Stock |
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| 100MG | 578 | In Stock |
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| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameIM156
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NoteResearch use only, not for human use.
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Brief DescriptionIM156 is an orally bioavailable mitochondrial oxidative phosphorylation (OxPhos) inhibitor, with potential antineoplastic activity.
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DescriptionIM156 is an orally bioavailable mitochondrial oxidative phosphorylation (OxPhos) inhibitor, with potential antineoplastic activity. IM156, a new metformin derivative, formerly known as HL156A, has been reported to ameliorate various types of fibrosis and inhibit in vitro and in vivo tumors by inducing AMPK activation more potently than metformin. In vivo treatment of IM156 exacerbated the memory differentiation of virus-specific CD8+ T cells, resulting in an increase in short-lived effector cells but decrease in memory precursor effector cells. Thus, IM156 treatment impaired the function of virus-specific memory CD8+ T cells, indicating that excessive AMPK activation weakens memory T cell differentiation, thereby suppressing recall immune responses.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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Recptoroxidative phosphorylation (OXPHOS)
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Research Area——
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Indication——
Chemical Information
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CAS Number1422365-93-2
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Formula Weight315.13
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Molecular FormulaC13H16F3N5O?
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Purity>98% (HPLC)
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Solubility——
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SMILESFC(F)(F)Oc1ccc(NC(=N)NC(=N)N2CCCC2)cc1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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