HQNO

CAS No. 341-88-8

HQNO( —— )

Catalog No. M22043 CAS No. 341-88-8

HQNO is a natural product isolated from P. aeruginosa,and is a potent inhibitor of electron transport chain(Kd of 64 nM for complex III).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 85 In Stock
5MG 48 In Stock
10MG 76 In Stock
25MG 141 In Stock
50MG 245 In Stock
100MG 423 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    HQNO
  • Note
    Research use only, not for human use.
  • Brief Description
    HQNO is a natural product isolated from P. aeruginosa,and is a potent inhibitor of electron transport chain(Kd of 64 nM for complex III).
  • Description
    HQNO is a natural product isolated from P. aeruginosa,and is a potent inhibitor of electron transport chain(Kd of 64 nM for complex III). It also is a potent mitochondrial NDH-2 inhibitorin many species.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    mitochondrial NDH-2
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    341-88-8
  • Formula Weight
    259.34
  • Molecular Formula
    C16H21NO2
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 5 mg/mL (19.28 mM)
  • SMILES
    CCCCCCCC1=CC(=O)C2=CC=CC=C2N1O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Jessica Petri, et al. Structure of the NDH-2 - HQNO Inhibited Complex Provides Molecular Insight Into Quinone-Binding Site Inhibitors. Biochim Biophys Acta Bioenerg. 2018 Jul;1859(7):482-490.2. Kang J , Kim Y J . HQNO-sensitive NADH:Quinone Oxidoreductase of Bacillus cereus KCTC 3674[J]. J Biochem Mol Biol, 2007, 40(1):53-57.
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