Centhaquine

CAS No. 57961-90-7

Centhaquine( Centhaquine,PMZ-2010 )

Catalog No. M22037 CAS No. 57961-90-7

Centhaquine is an adrenergic receptor potentially for the treatment of postoperative pain and for the resuscitation of hypovolemic shock.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 59 In Stock
2MG 33 In Stock
5MG 53 In Stock
10MG 89 In Stock
25MG 180 In Stock
50MG 275 In Stock
100MG 423 In Stock
200MG 609 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Centhaquine
  • Note
    Research use only, not for human use.
  • Brief Description
    Centhaquine is an adrenergic receptor potentially for the treatment of postoperative pain and for the resuscitation of hypovolemic shock.
  • Description
    Centhaquine is an adrenergic receptor potentially for the treatment of postoperative pain and for the resuscitation of hypovolemic shock.(In Vivo):Centhaquine (Centhaquin) (intravenous injection, 0.01-1.0 mg/kg; intraduodenal administration 1.0-2.5 mg/kg) lowers the blood pressure and reduced the heart rate of anaesthetized and unanaesthetized (decerebrate) cat in a dose-dependent manner.Centhaquine (Centhaquin) (intravertebral arterial injection; 5-10 μg) or by topical application to the exposed ventral surface of medulla or floor of the fourth ventricle causes hypotension and bradycardia as well as reduced the excitability of the vasomotor loci.Centhaquine (Centhaquin;PMZ-2010) (intravenous administration; 0.015mg/kg) can attenuate the deleterious effects of catecholamines, improving both the macro- and microcirculation during CPR.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    Centhaquine,PMZ-2010
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    Others
  • Indication
    Hypovolemic Shock

Chemical Information

  • CAS Number
    57961-90-7
  • Formula Weight
    331.45
  • Molecular Formula
    C22H25N3
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:60 mg/mL (181.02 mM; Need ultrasonic)
  • SMILES
    CC1=CC(=CC=C1)N1CCN(CCC2=NC3=CC=CC=C3C=C2)CC1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Papalexopoulou K, et al. Centhaquin Effects in a Swine Model of Ventricular Fibrillation: Centhaquin and Cardiac Arrest.Heart Lung Circ. 2017 Aug;26(8):856-863.
molnova catalog
related products
  • Mephenesin

    Mephenesin is an NMDA receptor antagonist, is a centrally acting muscle relaxant.

  • 1-Phenylethanol

    1-Phenylethanol has a nongenotoxic mode of action responsible for the lung and liver tumors observed in mice following 2 years of inhalation exposure to ethylbenzene.

  • Hydroxy-β-sanshool

    Hydroxy-β-sanshool is a pungent compound obtained from Zanthoxylum piperitum.