LQZ-7I

Research use only, not for human use.

LQZ-7I is an inhibitor of surviving-targeting. It orally effectively inhibits xenograft tumor growth and induces survivin loss in tumors.

LQZ-7I is an inhibitor of surviving-targeting. It orally effectively inhibits xenograft tumor growth and induces survivin loss in tumors.

Western Blot Analysis Cell Line:PC-3 or C4-2 cells Concentration:10 μM Incubation Time:0-6 hours Result:Reduced the expression of survivin.

Animal Model:6-week old male NSG mice Dosage:100 mg/kg; 200 μL vehicle (90% corn oil/10% DMSO) Administration:Oral gavage every other day for a total of ten treatments Result:Significantly suppressed tumor growth without any notable adverse effect on the mice as indicated by lacking changes in body weight and in wet weight of major organs at the end of the study.

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Others

Other Targets

Survivin

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195822-23-2

348.35

C20H14F2N4

>98% (HPLC)

DMSO:120mg/ml (344.48 Mm; Need ultrasonic)

FC1=CC=C(NC2=NC3=CC=CC=C3N=C2NC2=CC=C(F)C=C2)C=C1

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(-20℃)

With Ice Pack

≥ 2 years