Cart
sales@molnova.com
Home - Products - Cell Cycle/DNA Damage - Potassium Channel - IK1 inhibitor PA-6

IK1 inhibitor PA-6

CAS No. 500715-03-7

IK1 inhibitor PA-6( —— )

Catalog No. M22001 CAS No. 500715-03-7

IK1 inhibitor PA-6 (PA-6) is a selective and potent inhibitor of IK1.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 57 In Stock
2MG 32 In Stock
5MG 51 In Stock
10MG 100 In Stock
25MG 188 In Stock
50MG 312 In Stock
100MG 458 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    IK1 inhibitor PA-6
  • Note
    Research use only, not for human use.
  • Brief Description
    IK1 inhibitor PA-6 (PA-6) is a selective and potent inhibitor of IK1.
  • Description
    IK1 inhibitor PA-6 (PA-6) is a selective and potent inhibitor of IK1 (KIR2.x ion-channel-carried inward rectifier current)(IC50 of 12-15 nM for human and mouse KIR2.x currents).
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    Potassium Channel
  • Recptor
    KIR2.x currents
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    500715-03-7
  • Formula Weight
    492.62
  • Molecular Formula
    C31H32N4O2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:120mg/ml (243.59 Mm; Need ultrasonic)
  • SMILES
    N=C(NC1=CC=C(OCCCCCOC2=CC=C(NC(=N)C3=CC=CC=C3)C=C2)C=C1)C1=CC=CC=C1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Ji Y, et al. The inward rectifier current inhibitor PA-6 terminates atrial fibrillation and does not cause ventricular arrhythmias in goat and dog models. Br J Pharmacol. 2017 Aug;174(15):2576-2590.2. Ji Y, et al. PA-6 inhibits inward rectifier currents carried by V93I and D172N gain-of-function KIR2.1 channels, but increases channel protein expression. J Biomed Sci. 2017 Jul 15;24(1):44.
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • BL-1249

    BL-1249 is a selective and potent non-steroidal potassium channel activator with anti-inflammatory activity that activates K2P2.1 (TREK-1) and K2P10.1 (TREK-2).

  • VU590

    VU590 is a potent and moderately selective inhibitor of extrarenal medullary potassium ROMK (Kir1.1) that also inhibits Kir7.1 and modulates uterine myometrial contractility and melanocortin signalling.

  • GAL-021 sulfate

    GAL-021 sulfate is a BKCa channel blocker that inhibits the analgesic effects of opioids and is used in the study of respiratory control diseases.

Sign In Join Free