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IK1 inhibitor PA-6
CAS No. 500715-03-7
IK1 inhibitor PA-6( —— )
Catalog No. M22001 CAS No. 500715-03-7
IK1 inhibitor PA-6 (PA-6) is a selective and potent inhibitor of IK1.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 57 | In Stock |
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| 2MG | 32 | In Stock |
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| 5MG | 51 | In Stock |
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| 10MG | 100 | In Stock |
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| 25MG | 188 | In Stock |
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| 50MG | 312 | In Stock |
|
| 100MG | 458 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameIK1 inhibitor PA-6
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NoteResearch use only, not for human use.
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Brief DescriptionIK1 inhibitor PA-6 (PA-6) is a selective and potent inhibitor of IK1.
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DescriptionIK1 inhibitor PA-6 (PA-6) is a selective and potent inhibitor of IK1 (KIR2.x ion-channel-carried inward rectifier current)(IC50 of 12-15 nM for human and mouse KIR2.x currents).
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayCell Cycle/DNA Damage
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TargetPotassium Channel
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RecptorKIR2.x currents
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Research Area——
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Indication——
Chemical Information
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CAS Number500715-03-7
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Formula Weight492.62
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Molecular FormulaC31H32N4O2
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Purity>98% (HPLC)
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SolubilityDMSO:120mg/ml (243.59 Mm; Need ultrasonic)
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SMILESN=C(NC1=CC=C(OCCCCCOC2=CC=C(NC(=N)C3=CC=CC=C3)C=C2)C=C1)C1=CC=CC=C1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Ji Y, et al. The inward rectifier current inhibitor PA-6 terminates atrial fibrillation and does not cause ventricular arrhythmias in goat and dog models. Br J Pharmacol. 2017 Aug;174(15):2576-2590.2. Ji Y, et al. PA-6 inhibits inward rectifier currents carried by V93I and D172N gain-of-function KIR2.1 channels, but increases channel protein expression. J Biomed Sci. 2017 Jul 15;24(1):44.
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