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JNK Inhibitor VIII
CAS No. 894804-07-0
JNK Inhibitor VIII( TCS JNK 6o )
Catalog No. M21993 CAS No. 894804-07-0
JNK Inhibitor VIII is an ATP-competitive selective inhibitor of c-Jun N-terminal kinase (JNK)(IC50 values of 45 nM and 160 nM for JNK-1 and -2, respectively).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 126 | In Stock |
|
| 5MG | 116 | In Stock |
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| 10MG | 187 | In Stock |
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| 25MG | 330 | In Stock |
|
| 50MG | 480 | In Stock |
|
| 100MG | 684 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameJNK Inhibitor VIII
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NoteResearch use only, not for human use.
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Brief DescriptionJNK Inhibitor VIII is an ATP-competitive selective inhibitor of c-Jun N-terminal kinase (JNK)(IC50 values of 45 nM and 160 nM for JNK-1 and -2, respectively).
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DescriptionJNK Inhibitor VIII is an ATP-competitive selective inhibitor of c-Jun N-terminal kinase (JNK)(IC50 values of 45 nM and 160 nM for JNK-1 and -2, respectively).
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In Vitro——
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In Vivo——
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SynonymsTCS JNK 6o
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PathwayMAPK/ERK Signaling
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TargetJNK
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RecptorJNK1:2 nM (Ki)|JNK1:45 nM (IC50)|JNK2:4 nM (Ki)|JNK2:160 nM (IC50)|JNK3:52 nM (Ki)
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Research Area——
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Indication——
Chemical Information
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CAS Number894804-07-0
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Formula Weight356.38
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Molecular FormulaC18H20N4O4
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 250 mg/mL (701.50 mM)
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SMILESCCOc1nc(NC(=O)Cc2cc(OC)ccc2OC)cc(N)c1C#N
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Szczepankiewicz BG, et al. Aminopyridine-based c-Jun N-terminal kinase inhibitors with cellular activity and minimal cross-kinase activity. J Med Chem. 2006 Jun 15;49(12):3563-80.
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