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ML188
CAS No. 1417700-13-0
ML188( —— )
Catalog No. M21931 CAS No. 1417700-13-0
ML188 is a selective noncovalent SARS-CoV 3CLpro inhibitor(IC50 : 1.5 μM), with moderate MW and good enzyme and antiviral inhibitory activity.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 188 | In Stock |
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| 5MG | 168 | In Stock |
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| 10MG | 246 | In Stock |
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| 25MG | 417 | In Stock |
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| 50MG | 604 | In Stock |
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| 100MG | 858 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameML188
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NoteResearch use only, not for human use.
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Brief DescriptionML188 is a selective noncovalent SARS-CoV 3CLpro inhibitor(IC50 : 1.5 μM), with moderate MW and good enzyme and antiviral inhibitory activity.
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DescriptionML188 is a selective noncovalent SARS-CoV 3CLpro inhibitor(IC50 : 1.5 μM), with moderate MW and good enzyme and antiviral inhibitory activity.Probe 16-(R) (ML188) is a modest molecular weight SARS-CoV 3CLpro inhibitor with demonstrated antiviral activity and a non-covalent mechanism of action.
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In VitroML188 (0-30 μM; 48 hours) effectively inhibit SARS-CoV replication in cell culture.Probe ML188 is a modest molecular weight SARS-CoV 3CLpro inhibitor with demonstrated antiviral activity and a non-covalent mechanism of action. ML188 yields an antiviral EC50 value ranging from 12.9 to 13.4 μM in mock-infected and SARS-CoV infected cells. Cell Viability Assay Cell Line:Vero E6 cells (mock-infected or infected with SARS-CoV)Concentration:3, 4, 5, 8,10, 15, 20, 30 μM Incubation Time:48 hour Result:Against mock-infected and SARS-CoV infected cells.
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorSARS-CoV
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Research Area——
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Indication——
Chemical Information
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CAS Number1417700-13-0
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Formula Weight433.54
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Molecular FormulaC26H31N3O3
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 250 mg/mL (576.65 mM)
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SMILESCC(C)(C)NC(=O)[C@H](N(C(=O)c1ccco1)c1ccc(cc1)C(C)(C)C)c1cccnc1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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Haspin-IN-3
Haspin-IN-3 is a potent haspin inhibitor with an IC50 of 14 nM.Haspin-IN-3 has anticancer activity.
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AZ876
AZ876 is a potent highly selective LXR agonist with Ki/EC50 of 7/6 nM and 11/73 nM for hLXRα and hLXRβ respectively.
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Ocimene
Beta-Ocimene is a naturally occurring organic compound that belongs to the terpene family. It exists as a mixture of three isomers: cis β-Ocimene, trans β-Ocimene and myrcene-like β-Ocimene. It has a pleasant, sweet herbaceous scent and is found in many plants, including mint, basil, parsley, and kumquat. β-Ocimene is widely used in the flavor and fragrance industry due to its characteristic aroma and taste. It also has potential applications in agriculture as natural insect repellants and pheromones that attract beneficial insects. β-Ocimene has potential anti-inflammatory and anticancer activities.
