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BMS-986251
CAS No. 2041841-30-7
BMS-986251( —— )
Catalog No. M21869 CAS No. 2041841-30-7
BMS-986251 is a Clinically Viable, Potent, and Selective RORγt Inverse Agonist.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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| 100MG | Get Quote | Get Quote |
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| 500MG | Get Quote | Get Quote |
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Biological Information
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Product NameBMS-986251
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NoteResearch use only, not for human use.
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Brief DescriptionBMS-986251 is a Clinically Viable, Potent, and Selective RORγt Inverse Agonist.
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DescriptionBMS-986251 is a Clinically Viable, Potent, and Selective RORγt Inverse Agonist. BMS-986251 displayed dose-dependent inhibition of IL-17F production in a mouse IL-2/IL-23 stimulated pharmacodynamic model. BMS-986251 was studied in mouse acanthosis and imiquimod-induced models of skin inflammation, where it demonstrated robust efficacy comparable to a positive control.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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Recptor——
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Research Area——
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Indication——
Chemical Information
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CAS Number2041841-30-7
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Formula Weight667.61
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Molecular FormulaC30H29F8NO5S
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Purity>98% (HPLC)
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Solubility——
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SMILESFC(C(F)(F)F)(C(F)(F)F)C1=CC2=C(C=C1)[C@@]3(S(=O)(C4=CC=C(F)C=C4)=O)[C@@](N(C([C@@H]5CC[C@@H](C(O)=O)C[C@@H]5C)=O)CC3)([H])CC2
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Chemical Name(1R,3S,4R)-4-((3aR,9bR)-9b-((4-fluorophenyl)sulfonyl)-7-(perfluoropropan-2-yl)- 2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole-3-carbonyl)-3-methylcyclohexane-1-carboxylic acid
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
molnova catalog
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