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Dehydroeburicoic acid

CAS No. 6879-05-6

Dehydroeburicoic acid( —— )

Catalog No. M21680 CAS No. 6879-05-6

Dehydroeburicoic acid induces necrotic cell death that involves Ca(2+) overload mitochondrial dysfunction and calpain activation in human glioblastomas.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Dehydroeburicoic acid
  • Note
    Research use only, not for human use.
  • Brief Description
    Dehydroeburicoic acid induces necrotic cell death that involves Ca(2+) overload mitochondrial dysfunction and calpain activation in human glioblastomas.
  • Description
    Dehydroeburicoic acid induces necrotic cell death that involves Ca(2+) overload mitochondrial dysfunction and calpain activation in human glioblastomas.
  • In Vitro
    Dehydrotrametenolic acid selectively inhibits the growth of H-ras transformed cells with a GI50 value of 40 μM.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Immunology/Inflammation
  • Target
    NOS
  • Recptor
    NO Synthase|TNF-α|NOS
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    6879-05-6
  • Formula Weight
    468.73
  • Molecular Formula
    C3lH48O3
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 1 mg/mL (2.13 mM)
  • SMILES
    CC(C)C(=C)CC[C@H]([C@H]1CC[C@@]2([C@@]1(CC=C3C2=CC[C@@H]4[C@@]3(CC[C@@H](C4(C)C)O)C)C)C)C(=O)O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Dehydroeburicoic acid induces calcium- and calpain-dependent necrosis in human U87MG glioblastomas.Chem Res Toxicol. 2009 Nov;22(11):1817-26.
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