BNC210( H-Ile-Trp-OH | IW-2143 )

Catalog No. M21627 CAS No. 13589-06-5

BNC210 is a α7 nAChR negative allosteric modulator. BNC210 has potent activity in animal models of anxiety and depression.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
1 mL x 10 mM in DMSO	28	In Stock
25MG	39	In Stock
50MG	63	In Stock
100MG	91	In Stock
200MG	Get Quote	In Stock
500MG	Get Quote	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

BNC210
Note

Research use only, not for human use.
Brief Description

BNC210 is a α7 nAChR negative allosteric modulator. BNC210 has potent activity in animal models of anxiety and depression.
Description

BNC210 is a α7 nAChR negative allosteric modulator. BNC210 has potent activity in animal models of anxiety and depression.
In Vitro

——
In Vivo

——
Synonyms

H-Ile-Trp-OH | IW-2143
Pathway

Endocrinology/Hormones
Target

AChR
Recptor

α7 nAChR
Research Area

Neurological Disease
Indication

Post-Traumatic Stress Disorder

Chemical Information

CAS Number

13589-06-5
Formula Weight

317.38
Molecular Formula

C17H23N3O3
Purity

>98% (HPLC)
Solubility

DMSO:125 mg/mL (393.85 mM; Need ultrasonic)
SMILES

CC[C@H](C)[C@H](N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Toby Wise Fiona Patrick Nicholas Meyeret al.Cholinergic Modulation of Disorder-Relevant Neural Circuits in Generalized Anxiety Disorder.Biol Psychiatry. 2020 May 15;87(10):908-915.

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