Cart
sales@molnova.com
BIO-013077-01
CAS No. 746667-48-1
BIO-013077-01( —— )
Catalog No. M21624 CAS No. 746667-48-1
BIO-013077-01 is a potent TGFbeta family type I receptors antagonist.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 133 | In Stock |
|
| 5MG | 88 | In Stock |
|
| 10MG | 136 | In Stock |
|
| 25MG | 273 | In Stock |
|
| 50MG | 384 | In Stock |
|
| 100MG | 545 | In Stock |
|
| 200MG | 737 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameBIO-013077-01
-
NoteResearch use only, not for human use.
-
Brief DescriptionBIO-013077-01 is a potent TGFbeta family type I receptors antagonist.
-
DescriptionBIO-013077-01 is a potent TGFbeta family type I receptors antagonist.
-
In VitroA wide range of cellular functions such as cell proliferation, differentiation, adhesion, migration, and apoptosis are regulated by TGF-β superfamily members. The TGF-βs include the three major TGF-β isoforms, TGF-β1, TGF-β2, and TGF-β3 which are expressed in mammals. TGF-β transduces signals through a complex of two related but structurally and functionally distinct serine/threonine kinase receptors, termed type 1 and type II. Deregulation of TGF-β signaling has been also implicated in various human diseases including cancer, pancreatic diseases, and hematological malignancies.
-
In Vivo——
-
Synonyms——
-
PathwayOthers
-
TargetOther Targets
-
RecptorTGFβ
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number746667-48-1
-
Formula Weight287.32
-
Molecular FormulaC17H13N5
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 100 mg/mL (348.04 mM)
-
SMILESCc1cccc(n1)-c1n[nH]cc1-c1ccc2nccnc2c1
-
Chemical Name6-[3-(6-Methylpyridin-2-yl)-1H-pyrazol-4-yl]quinoxaline
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Koike R Uchiyama T Arimoto-Kobayashi S Okamoto K Negishi T. Increase of somatic cell mutations in oxidative damage-sensitive drosophila. Genes Environ. 2018 Jan 10;40:3.
molnova catalog
related products
-
Netilmicin sulfate
Netilmicin Sulfate is a member of the aminoglycoside family of antibiotics.
-
Zwittergent 3-16
ZWITTERGENT 3-16 Detergent is a quaternary ammonium surfactant, emulsifier, foaming and wetting agent commonly used in the skin care industry.ZWITTERGENT 3-16 Detergent is involved in protein purification.
-
Anthrone
Anthrone is an organic compound commonly used as a dye and intermediate. It can be used to make products such as pigments, dyes and fluorescent whitening agents, and is widely used in certain industrial production fields such as textile manufacturing, soap making and paper making. In addition, this compound is also used as a reagent and catalyst in some organic synthesis reactions.
