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Cyclopentolate Hydrochloride

CAS No. 5870-29-1

Cyclopentolate Hydrochloride( —— )

Catalog No. M21588 CAS No. 5870-29-1

Cyclopentolate Hydrochloride is a muscarinic acetylcholine receptors antagonist with Kis of 1.62 27.5 and 2.63 nM for M1 M2 and M3 receptors respectively.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Cyclopentolate Hydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    Cyclopentolate Hydrochloride is a muscarinic acetylcholine receptors antagonist with Kis of 1.62 27.5 and 2.63 nM for M1 M2 and M3 receptors respectively.
  • Description
    Cyclopentolate Hydrochloride is a muscarinic acetylcholine receptors antagonist with Kis of 1.62 27.5 and 2.63 nM for M1 M2 and M3 receptors respectively.(In Vivo):Survival in rats pretreated with cyclopentolate (20 mg/kg) is 90%.
  • In Vitro
    ——
  • In Vivo
    Survival in rats pretreated with cyclopentolate (20 mg/kg) is 90%. Animal Model:Eighty Sprague-Dawley rats (acute, lethal organophosphate pesticide (OP) poisoning model)Dosage:20 mg/kg (Ophthalmic cyclopentolate)Administration:i.p.Result:Survival in rats pretreated with ophthalmic cyclopentolate (20 mg/kg) is 90%.
  • Synonyms
    ——
  • Pathway
    Endocrinology/Hormones
  • Target
    AChR
  • Recptor
    M5 mAChR
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    5870-29-1
  • Formula Weight
    327.85
  • Molecular Formula
    C17H26ClNO3
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 250 mg/mL (762.54 mM)
  • SMILES
    Cl.CN(C)CCOC(=O)C(c1ccccc1)C1(O)CCCC1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Ishikawa H Desantis L Patil P N . Selectivity of Muscarinic Agonists Including (±)-Aceclidine and Antimuscarinics on the Human Intraocular Muscles[J]. Journal of Ocular Pharmacology & Therapeutics 1998 14(4):363-373.
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