Butyl isobutyl phthalate

CAS No. 17851-53-5

Butyl isobutyl phthalate( ButylIsobutylPhthalate )

Catalog No. M21572 CAS No. 17851-53-5

Butyl isobutyl phthalate is a non-competitive α-glucosidase inhibitor(IC50 :38 μM)it shows a hypoglycemic effect.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 48 In Stock
10MG 29 In Stock
25MG 46 In Stock
50MG 67 In Stock
100MG 113 In Stock
200MG Get Quote In Stock
500MG 276 In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Butyl isobutyl phthalate
  • Note
    Research use only, not for human use.
  • Brief Description
    Butyl isobutyl phthalate is a non-competitive α-glucosidase inhibitor(IC50 :38 μM)it shows a hypoglycemic effect.
  • Description
    Butyl isobutyl phthalate is a non-competitive α-glucosidase inhibitor(IC50 :38 μM)it shows a hypoglycemic effect.
  • In Vitro
    Butyl isobutyl phthalate exhibits significant, concentration-dependent inhibitory activity against α-glucosidase with an IC50 value of 38 μM.
  • In Vivo
    Butyl isobutyl phthalate (intragastric administration; 25, 50 or 100 mg/kg; 3 days) results in a more significant reduction in the blood glucose level, with the concentration of blood glucose being 11.50, 8.60 and 6.50 mM, respectively. Animal Model:Streptozocin induced diabetic mice (Male Kunming mice)Dosage:25, 50 or 100 mg/kg Administration:Intragastric administration Result:Had the observed antidiabetes activity in mice.
  • Synonyms
    ButylIsobutylPhthalate
  • Pathway
    Cytoskeleton/Cell Adhesion Molecules
  • Target
    Glucokinase
  • Recptor
    α-glucosidase
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    17851-53-5
  • Formula Weight
    278.34
  • Molecular Formula
    C16H22O4
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:250 mg/mL (898.18 mM)
  • SMILES
    CCCCOC(=O)c1ccccc1C(=O)OCC(C)C
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Bu T Liu M Zheng L et al. α‐glucosidase inhibition and the in vivo hypoglycemic effect of butyl‐isobutyl‐phthalate derived from the Laminaria japonica rhizoid[J]. Phytotherapy Research 2010 24(11).
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