Butyl isobutyl phthalate

CAS No. 17851-53-5

Butyl isobutyl phthalate( ButylIsobutylPhthalate )

Catalog No. M21572 CAS No. 17851-53-5

Butyl isobutyl phthalate is a non-competitive α-glucosidase inhibitor(IC50 :38 μM)it shows a hypoglycemic effect.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
10MG 28 In Stock
25MG 43 In Stock
50MG 65 In Stock
100MG 110 In Stock
500MG 267 In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Butyl isobutyl phthalate
  • Note
    Research use only, not for human use.
  • Brief Description
    Butyl isobutyl phthalate is a non-competitive α-glucosidase inhibitor(IC50 :38 μM)it shows a hypoglycemic effect.
  • Description
    Butyl isobutyl phthalate is a non-competitive α-glucosidase inhibitor(IC50 :38 μM)it shows a hypoglycemic effect.
  • In Vitro
    Butyl isobutyl phthalate exhibits significant, concentration-dependent inhibitory activity against α-glucosidase with an IC50 value of 38 μM.
  • In Vivo
    Butyl isobutyl phthalate (intragastric administration; 25, 50 or 100 mg/kg; 3 days) results in a more significant reduction in the blood glucose level, with the concentration of blood glucose being 11.50, 8.60 and 6.50 mM, respectively. Animal Model:Streptozocin induced diabetic mice (Male Kunming mice)Dosage:25, 50 or 100 mg/kg Administration:Intragastric administration Result:Had the observed antidiabetes activity in mice.
  • Synonyms
    ButylIsobutylPhthalate
  • Pathway
    Cytoskeleton/Cell Adhesion Molecules
  • Target
    Glucokinase
  • Recptor
    α-glucosidase
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    17851-53-5
  • Formula Weight
    278.34
  • Molecular Formula
    C16H22O4
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:250 mg/mL (898.18 mM)
  • SMILES
    CCCCOC(=O)c1ccccc1C(=O)OCC(C)C
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Bu T Liu M Zheng L et al. α‐glucosidase inhibition and the in vivo hypoglycemic effect of butyl‐isobutyl‐phthalate derived from the Laminaria japonica rhizoid[J]. Phytotherapy Research 2010 24(11).
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