Butyl isobutyl phthalate

Research use only, not for human use.

Butyl isobutyl phthalate is a non-competitive α-glucosidase inhibitor(IC50 :38 μM)it shows a hypoglycemic effect.

Butyl isobutyl phthalate is a non-competitive α-glucosidase inhibitor(IC50 :38 μM)it shows a hypoglycemic effect.

Butyl isobutyl phthalate exhibits significant, concentration-dependent inhibitory activity against α-glucosidase with an IC50 value of 38 μM.

Butyl isobutyl phthalate (intragastric administration; 25, 50 or 100 mg/kg; 3 days) results in a more significant reduction in the blood glucose level, with the concentration of blood glucose being 11.50, 8.60 and 6.50 mM, respectively. Animal Model:Streptozocin induced diabetic mice (Male Kunming mice)Dosage:25, 50 or 100 mg/kg Administration:Intragastric administration Result:Had the observed antidiabetes activity in mice.

ButylIsobutylPhthalate

Cytoskeleton/Cell Adhesion Molecules

Glucokinase

α-glucosidase

——

——

17851-53-5

278.34

C16H22O4

>98% (HPLC)

DMSO:250 mg/mL (898.18 mM)

CCCCOC(=O)c1ccccc1C(=O)OCC(C)C

——

(-20℃)

With Ice Pack

≥ 2 years