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Quercetagetin

CAS No. 90-18-6

Quercetagetin( 6-Hydroxyquercetin )

Catalog No. M21534 CAS No. 90-18-6

Quercetagetin (6-Hydroxyquercetin) is the major flavonoid isolated from Citrus unshiu. It is a moderately potent and selective cell-permeable pim-1 kinase inhibitor (IC50: 0.34 μM).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 214 In Stock
5MG 202 In Stock
10MG 302 In Stock
25MG 509 In Stock
50MG 718 In Stock
100MG 977 In Stock
200MG Get Quote In Stock
500MG 1944 In Stock
1G Get Quote In Stock
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Biological Information

  • Product Name
    Quercetagetin
  • Note
    Research use only, not for human use.
  • Brief Description
    Quercetagetin (6-Hydroxyquercetin) is the major flavonoid isolated from Citrus unshiu. It is a moderately potent and selective cell-permeable pim-1 kinase inhibitor (IC50: 0.34 μM).
  • Description
    Quercetagetin (6-Hydroxyquercetin) is the major flavonoid isolated from Citrus unshiu. It is a moderately potent and selective cell-permeable pim-1 kinase inhibitor (IC50: 0.34 μM).
  • In Vitro
    Cell Viability Assay Cell Line:RWPE2 prostate cancer cells Concentration:0.1, 1, 10, and 100 μM Incubation Time:72 hours Result:Inhibited growth of RWPE2 prostate cancer cells with average ED50 is 3.8 μM.
  • In Vivo
    Animal Model:SKH-1 hairless mice modelDosage:4 or 20 nmol Administration:Topical application; 28 weeks Result:Inhibited UVB-induced skin tumorigenesis in SKH-1 hairless mice models. Delayed the development of tumors and reduced tumor volumes in an SKH-1 hairless mice model.
  • Synonyms
    6-Hydroxyquercetin
  • Pathway
    JAK/STAT Signaling
  • Target
    Pim
  • Recptor
    Pim1
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    90-18-6
  • Formula Weight
    318.23
  • Molecular Formula
    C15H10O8
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:125 mg/mL (392.79 mM)
  • SMILES
    Oc(ccc(C(Oc(c(C1=O)c2O)cc(O)c2O)=C1O)c1)c1O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Yang X et al. Isolation and identification of an antioxidant flavonoid compound from citrus-processing by-product. J Sci Food Agric. 2011 Aug 15;91(10):1925-7.
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