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Quercetagetin
CAS No. 90-18-6
Quercetagetin( 6-Hydroxyquercetin )
Catalog No. M21534 CAS No. 90-18-6
Quercetagetin (6-Hydroxyquercetin) is the major flavonoid isolated from Citrus unshiu. It is a moderately potent and selective cell-permeable pim-1 kinase inhibitor (IC50: 0.34 μM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 214 | In Stock |
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| 5MG | 202 | In Stock |
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| 10MG | 302 | In Stock |
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| 25MG | 509 | In Stock |
|
| 50MG | 718 | In Stock |
|
| 100MG | 977 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | 1944 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameQuercetagetin
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NoteResearch use only, not for human use.
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Brief DescriptionQuercetagetin (6-Hydroxyquercetin) is the major flavonoid isolated from Citrus unshiu. It is a moderately potent and selective cell-permeable pim-1 kinase inhibitor (IC50: 0.34 μM).
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DescriptionQuercetagetin (6-Hydroxyquercetin) is the major flavonoid isolated from Citrus unshiu. It is a moderately potent and selective cell-permeable pim-1 kinase inhibitor (IC50: 0.34 μM).
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In VitroCell Viability Assay Cell Line:RWPE2 prostate cancer cells Concentration:0.1, 1, 10, and 100 μM Incubation Time:72 hours Result:Inhibited growth of RWPE2 prostate cancer cells with average ED50 is 3.8 μM.
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In VivoAnimal Model:SKH-1 hairless mice modelDosage:4 or 20 nmol Administration:Topical application; 28 weeks Result:Inhibited UVB-induced skin tumorigenesis in SKH-1 hairless mice models. Delayed the development of tumors and reduced tumor volumes in an SKH-1 hairless mice model.
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Synonyms6-Hydroxyquercetin
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PathwayJAK/STAT Signaling
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TargetPim
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RecptorPim1
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Research Area——
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Indication——
Chemical Information
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CAS Number90-18-6
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Formula Weight318.23
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Molecular FormulaC15H10O8
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Purity>98% (HPLC)
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SolubilityDMSO:125 mg/mL (392.79 mM)
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SMILESOc(ccc(C(Oc(c(C1=O)c2O)cc(O)c2O)=C1O)c1)c1O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Yang X et al. Isolation and identification of an antioxidant flavonoid compound from citrus-processing by-product. J Sci Food Agric. 2011 Aug 15;91(10):1925-7.
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