Cart
sales@molnova.com
Quercetagetin
CAS No. 90-18-6
Quercetagetin( 6-Hydroxyquercetin )
Catalog No. M21534 CAS No. 90-18-6
Quercetagetin (6-Hydroxyquercetin) is the major flavonoid isolated from Citrus unshiu. It is a moderately potent and selective cell-permeable pim-1 kinase inhibitor (IC50: 0.34 μM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 214 | In Stock |
|
| 5MG | 202 | In Stock |
|
| 10MG | 302 | In Stock |
|
| 25MG | 509 | In Stock |
|
| 50MG | 718 | In Stock |
|
| 100MG | 977 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | 1944 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameQuercetagetin
-
NoteResearch use only, not for human use.
-
Brief DescriptionQuercetagetin (6-Hydroxyquercetin) is the major flavonoid isolated from Citrus unshiu. It is a moderately potent and selective cell-permeable pim-1 kinase inhibitor (IC50: 0.34 μM).
-
DescriptionQuercetagetin (6-Hydroxyquercetin) is the major flavonoid isolated from Citrus unshiu. It is a moderately potent and selective cell-permeable pim-1 kinase inhibitor (IC50: 0.34 μM).
-
In VitroCell Viability Assay Cell Line:RWPE2 prostate cancer cells Concentration:0.1, 1, 10, and 100 μM Incubation Time:72 hours Result:Inhibited growth of RWPE2 prostate cancer cells with average ED50 is 3.8 μM.
-
In VivoAnimal Model:SKH-1 hairless mice modelDosage:4 or 20 nmol Administration:Topical application; 28 weeks Result:Inhibited UVB-induced skin tumorigenesis in SKH-1 hairless mice models. Delayed the development of tumors and reduced tumor volumes in an SKH-1 hairless mice model.
-
Synonyms6-Hydroxyquercetin
-
PathwayJAK/STAT Signaling
-
TargetPim
-
RecptorPim1
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number90-18-6
-
Formula Weight318.23
-
Molecular FormulaC15H10O8
-
Purity>98% (HPLC)
-
SolubilityDMSO:125 mg/mL (392.79 mM)
-
SMILESOc(ccc(C(Oc(c(C1=O)c2O)cc(O)c2O)=C1O)c1)c1O
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Yang X et al. Isolation and identification of an antioxidant flavonoid compound from citrus-processing by-product. J Sci Food Agric. 2011 Aug 15;91(10):1925-7.
molnova catalog
related products
-
Taprenepag
Taprenepag (CP-544326) is a potent and selective prostaglandin E2 receptor agonist (EC50 = 2.8 nM).
-
1-phenoxazin-10-ylet...
1-phenoxazin-10-ylethanone is a Pim-2 inhibitor. 1-phenoxazin-10-ylethanone induces apoptosis and autophagic cell death in triple-negative human breast cancer.
-
GNE-955
GNE-955 is a potent, selective pan-Pim inhibitor with Ki of 0.018/0.11/0.008 nM for Pim1/2/3, respectively.
