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4'57-Trimethoxyflavone
CAS No. 5631-70-9
4'57-Trimethoxyflavone( —— )
Catalog No. M21520 CAS No. 5631-70-9
574'-Trimethoxyflavone is isolated from Kaempferia parviflora (KP) which is a medicinal plant from Thailand.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 42 | In Stock |
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| 5MG | 38 | In Stock |
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| 10MG | 61 | In Stock |
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| 25MG | 128 | In Stock |
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| 50MG | 184 | In Stock |
|
| 100MG | 276 | In Stock |
|
| 200MG | 431 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product Name4'57-Trimethoxyflavone
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NoteResearch use only, not for human use.
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Brief Description574'-Trimethoxyflavone is isolated from Kaempferia parviflora (KP) which is a medicinal plant from Thailand.
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Description574'-Trimethoxyflavone is isolated from Kaempferia parviflora (KP) which is a medicinal plant from Thailand.
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In VitroCell Viability Assay Cell Line:AGS, SNU-1, SNU-16Concentration:12.5 ,25, 50, 100, 200 μM Incubation Time:24 and 48 h Result:Showed the highest cytotoxicity in SNU-16 cells.Apoptosis Analysis Cell Line: SNU-16 Concentration:12.5 ,25, 37.5, 50 μM Incubation Time:24 h Result:Increased the percentage of annexin V-positive SNU-16 cells from 7.2% to 58.0% and the expression of GRP78、IRE1a、ATF-4 and CHOP.Western Blot Analysis Cell Line:HDFs Concentration:6.25, 12.5 μM Incubation Time:24 h Result:Inhibited matrix metalloproteinase-1 ( MMP-1) expression and stimulated collagen, type I,and alpha 1 (COLIA1) expression.
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In Vivo——
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Synonyms——
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PathwayApoptosis
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TargetCaspase
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RecptorCaspase-3| PARP
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Research Area——
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Indication——
Chemical Information
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CAS Number5631-70-9
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Formula Weight312.3
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Molecular FormulaC18H16O5
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (320.18 mM)
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SMILESCOc(cc1)ccc1C(Oc1c2c(OC)cc(OC)c1)=CC2=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Kim H et al. Induction of ER Stress-Mediated Apoptosis by the Major Component 574'-TrimethoxyflavoneIsolated from Kaempferia parviflora Tea Infusion. Nutr Cancer. 2018 Aug-Sep;70(6):984-996.
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