Cart
sales@molnova.com
Home - Products - Others - Other Targets - Oxaceprol

Oxaceprol

CAS No. 33996-33-7

Oxaceprol( N-Acetyl-L-hydroxyproline )

Catalog No. M21329 CAS No. 33996-33-7

Oxaceprol is an established therapeutic agent for osteoarthritis.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
500MG 26 In Stock
1G Get Quote In Stock
Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    Oxaceprol
  • Note
    Research use only, not for human use.
  • Brief Description
    Oxaceprol is an established therapeutic agent for osteoarthritis.
  • Description
    Oxaceprol is an established therapeutic agent for osteoarthritis.(In Vitro):Oxaceprol, at 6 mg/kg/day for 7 days, significantly reduces both the surface area and wet weight of cotton pellet granulomas, being slightly less effective than indomethacin, 3 mg/kg.Oxaceprol (6–54 mg/kg/day) given therapeutically had no effect on the primary paw oedema response, but inhibits secondary lesions in the ears and tail.Oxaceprol does not inhibit the synthesis of prostaglandins in vitro, but markedly inhibits neutrophil infiltration into the joints of rats with adjuvant arthritis.
  • In Vitro
    ——
  • In Vivo
    Oxaceprol, at 6 mg/kg/day for 7 days, significantly reduces both the surface area and wet weight of cotton pellet granulomas, being slightly less effective than indomethacin, 3 mg/kg.Oxaceprol (6–54 mg/kg/day) given therapeutically had no effect on the primary paw oedema response, but inhibits secondary lesions in the ears and tail.Oxaceprol does not inhibit the synthesis of prostaglandins in vitro, but markedly inhibits neutrophil infiltration into the joints of rats with adjuvant arthritis. Animal Model:Male Sprague-Dawley rats.Dosage:18, 50 or 150 mg/kg.Administration:Gavage daily for 15 days.Result:Produced comparable inhibition of hyperalgesia to that produced by indomethacin.
  • Synonyms
    N-Acetyl-L-hydroxyproline
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    33996-33-7
  • Formula Weight
    173.17
  • Molecular Formula
    C7H11NO4
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:1 mg/mL (577.47 mM)
  • SMILES
    CC(=O)N1C[C@@H](C[C@H]1C(=O)O)O
  • Chemical Name
    (2S4R)-1-acetyl-4-hydroxypyrrolidine-2-carboxylic acid

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Ionac M Parnham M J Plauchithiu M et al. OXACEPROL AN ATYPICAL INHIBITOR OF INFLAMMATION AND JOINT DAMAGE[J]. pharmacological research 1996 33(6):367-373.
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • Calmodulin-Dependent...

    Calmodulin-Dependent Protein Kinase II (281-309) is a synthetic peptide that can be phosphorylated at Thr286 by PKC and inhibits CaM kinase II (IC50 = 80 nM).

  • GRP (18-27) (human, ...

    Neuromedin C porcine (GRP, 18-27, porcine) is a bombesin-like neuropeptide that can be obtained from porcine spinal cord. Neuromedin C porcine exhibits a potent contractile activity on rat uterus in the characteristic manner of bombesin. Neuromedin C porcine has research potential for neurological-related diseases.

  • Alclometasone diprop...

    Alclometasone dipropionate （Sch 22219） is a synthetic glucocorticoid, a steroidal compound with antiproliferative, anti-inflammatory, anti-allergic, antipruritic, and vasoconstrictive properties, which is used in the study of skin inflammation.

Sign In Join Free