D-Galactosamine HCl

CAS No. 1772-03-8

D-Galactosamine HCl( —— )

Catalog No. M21206 CAS No. 1772-03-8

D-Galactosamine HCl hepatotoxicity is associated with endotoxin sensitivity and mediated by lymphoreticular cells in mice.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    D-Galactosamine HCl
  • Note
    Research use only, not for human use.
  • Brief Description
    D-Galactosamine HCl hepatotoxicity is associated with endotoxin sensitivity and mediated by lymphoreticular cells in mice.
  • Description
    D-Galactosamine HCl hepatotoxicity is associated with endotoxin sensitivity and mediated by lymphoreticular cells in mice.
  • In Vitro
    ——
  • In Vivo
    Animal Model:C57BL/6J miceDosage:400 mg/kg, together with Lipopolysaccharide (HY-D1056) (LPS, 10 μg/kg) Administration:i.p.Result:Induces a model of acute liver failure, with necrosis in the liver.Increased serum ALT and AST levels and serum inflammatory cytokine concentrations, such as TNF-α, IFN-γ, IL-1β, IL-6, and IL-18.
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1772-03-8
  • Formula Weight
    215.63
  • Molecular Formula
    C6H14ClNO5
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:25mg/ml(215.63mM)
  • SMILES
    Cl.N[C@H]1C(O)O[C@H](CO)[C@H](O)[C@@H]1O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Chojkier M Fierer J . D-Galactosamine Ire atotoxicit Is Associated With Endotoxin Sensitivity and Mediated by Lymphoreticular Cells in Mice[J]. Gastroenterology 1985 88(1):115-121.
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