Bevantolol hydrochloride

CAS No. 42864-78-8

Bevantolol hydrochloride( NC-1400 hydrochloride )

Catalog No. M21186 CAS No. 42864-78-8

Bevantolol hydrochloride is a β1-adrenoceptor antagonist that treatment angina pectoris and hypertension.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
10MG 32 Get Quote
25MG 61 Get Quote
50MG 87 Get Quote
100MG 138 Get Quote
200MG 206 Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    Bevantolol hydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    Bevantolol hydrochloride is a β1-adrenoceptor antagonist that treatment angina pectoris and hypertension.
  • Description
    Bevantolol hydrochloride is a β1-adrenoceptor antagonist that treatment angina pectoris and hypertension.(In Vitro):Bevantolol hydrochloride has a pKi of 6.23 for β2-adrenergic receptor.(In Vivo):Bevantolol hydrochloride (200 mg/kg; PO by water; for 6 weeks) produces a significant decrease in the expression level of β1 adrenoceptor mRNA.
  • In Vitro
    Bevantolol hydrochloride has a pKi of 6.23 for β2-adrenergic receptor.
  • In Vivo
    Bevantolol hydrochloride (200 mg/kg; PO by water; for 6 weeks) produces a significant decrease in the expression level of β1 adrenoceptor mRNA. Animal Model:Male Wistar rats weighing 250-300 g Dosage:200 mg/kg Administration:PO by water; for 6 weeks Result:Produced a significant decrease in the expression level of β1 adrenoceptor mRNA.
  • Synonyms
    NC-1400 hydrochloride
  • Pathway
    Angiogenesis
  • Target
    Adrenergic Receptor
  • Recptor
    β1-adrenoceptor
  • Research Area
    Cardiovascular Disease
  • Indication
    Essential hypertension

Chemical Information

  • CAS Number
    42864-78-8
  • Formula Weight
    381.9
  • Molecular Formula
    C20H28ClNO4
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:76 mg/mL (199.01 mM)Ethanol:61 mg/mL (159.73 mM)H2O:52 mg/mL (136.16 mM)
  • SMILES
    COc1ccc(CCNCC(O)COc2cccc(C)c2)cc1OC.Cl
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Noshiro T Miura Y Yoshinaga K et al. Clinical evaluation of bevantolol hydrochloride in patients with severe hypertension. The Cooperative Study Group on Bevantolol in Japan[J]. International Journal of Clinical Pharmacology & Therapeutics 1995 33(4):240-245.
molnova catalog
related products
  • Methyl maslinate

    Methyl maslinate is an antagonist of β- adrenergic receptor with cardiotonic and antidysrhythmic properties. Methyl maslinate can be used in studies about hypertension.

  • ICI 89406

    ICI 89406 is a β-adrenergic antagonist.

  • Lutein

    Lutein has antitumour action, is potentially useful for treating macular degeneration.