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SP-13786

CAS No. 1448440-52-5

SP-13786( UAMC-1110 )

Catalog No. M21138 CAS No. 1448440-52-5

SP-13786 is an inhibitor of fibroblast activation protein (FAP) (IC50 : 3.2 nM); also inhibits prolyl oligopeptidase (PREP) ( IC50 : 1.8 μM).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 103 In Stock
5MG 93 In Stock
10MG 149 In Stock
25MG 278 In Stock
50MG 432 In Stock
100MG 693 In Stock
200MG 918 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
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Biological Information

  • Product Name
    SP-13786
  • Note
    Research use only, not for human use.
  • Brief Description
    SP-13786 is an inhibitor of fibroblast activation protein (FAP) (IC50 : 3.2 nM); also inhibits prolyl oligopeptidase (PREP) ( IC50 : 1.8 μM).
  • Description
    SP-13786 is an inhibitor of fibroblast activation protein (FAP) (IC50 : 3.2 nM); also inhibits prolyl oligopeptidase (PREP) ( IC50 : 1.8 μM).
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    UAMC-1110
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    FAP
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1448440-52-5
  • Formula Weight
    344.32
  • Molecular Formula
    C17H14F2N4O2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:100 mg/mL (290.43 mM; Need ultrasonic)
  • SMILES
    N#CC1CC(F)(F)CN1C(=O)CNC(=O)c1ccnc2ccccc12
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Jansen K Heirbaut L Verkerk R et al. Extended Structure–Activity Relationship and Pharmacokinetic Investigation of (4-Quinolinoyl)glycyl-2-cyanopyrrolidine Inhibitors of Fibroblast Activation Protein (FAP)[J]. Journal of Medicinal Chemistry 2014 57(7):3053-3074.
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