Hexa-D-arginine

CAS No. 673202-67-0

Hexa-D-arginine( —— )

Catalog No. M21017 CAS No. 673202-67-0

Hexa-D-arginine is an inhibitor of furinblocks the activation of Pseudomonas aeruginosa exotoxin A in vivo.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 147 In Stock
10MG 237 In Stock
25MG 402 In Stock
50MG 581 In Stock
100MG 799 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Hexa-D-arginine
  • Note
    Research use only, not for human use.
  • Brief Description
    Hexa-D-arginine is an inhibitor of furinblocks the activation of Pseudomonas aeruginosa exotoxin A in vivo.
  • Description
    Hexa-D-arginine is an inhibitor of furinblocks the activation of Pseudomonas aeruginosa exotoxin A in vivo.
  • In Vitro
    Hexa-D-arginine effectively blocks Pseudomonas aeruginosa exotoxin A (PEA)-induced cell lysis and is itself noncytotoxic.
  • In Vivo
    Administration of Hexa-D-arginine (0.1, 1, or 10 nM) to Pseudomonas aeruginosa exotoxin A (PEA)-treated mice (6-week-old FVB and 129/Sv mice) significantly improves their survival rate and also decreases circulating levels of TNF-α.
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    furin
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    673202-67-0
  • Formula Weight
    954.14
  • Molecular Formula
    C36H75N25O6
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?H2O : 50 mg/mL (52.40 mM)
  • SMILES
    C(C[C@H](C(=O)N[C@H](CCCN=C(N)N)C(=O)N[C@H](CCCN=C(N)N)C(=O)N[C@H](CCCN=C(N)N)C(=O)N[C@H](CCCN=C(N)N)C(=O)N[C@H](CCCN=C(N)N)C(=O)N)N)CN=C(N)N
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Sarac M S Cameron A Lindberg I . The Furin Inhibitor Hexa-D-Arginine Blocks the Activation of Pseudomonas aeruginosa Exotoxin A In Vivo[J]. Infection and Immunity 2002 70(12):7136-7139.
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