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5-Nitro-110-phenanthroline
CAS No. 4199-88-6
5-Nitro-110-phenanthroline( 5-NP )
Catalog No. M20958 CAS No. 4199-88-6
5-Nitro-110-phenanthroline(5-NP) is a potent bactericidal agent and inhibiting Clostridium difficile.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 28 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | 28 | In Stock |
|
| 500MG | 52 | In Stock |
|
| 1G | 83 | In Stock |
|
Biological Information
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Product Name5-Nitro-110-phenanthroline
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NoteResearch use only, not for human use.
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Brief Description5-Nitro-110-phenanthroline(5-NP) is a potent bactericidal agent and inhibiting Clostridium difficile.
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Description5-Nitro-110-phenanthroline(5-NP) is a potent bactericidal agent and inhibiting Clostridium difficile.
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In Vitro5-Nitro-1,10-phenanthroline (25 μM; 24 h) kills naturally resistant intracellular bacteria by inducing autophagy in THP-1 macrophages. 5-Nitro-1,10-phenanthroline (1x, 5x, 20x or 50x MIC, MIC=0.78 μM; 1 h) also modulates the host machinery to kill intracellular pathogens by inhibiting mycolic acid biosynthesis of Mtb. Cell Viability Assay Cell Line:Mtb H37Rv, M. bovis BCG and M. bovis BCG-5NP resistant strain Concentration:0-12.5 μM Incubation Time:24 hours Result:Inhibited pathogens with MIC99 values of 0.78 μM (Mtb H37Rv), 0.78 μM (M. bovis BCG), and >12.5 μM (M. bovis BCG-5NP), respectively.
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In Vivo——
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Synonyms5-NP
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PathwayGPCR/G Protein
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TargetAntibacterial
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RecptorBacterial
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Research Area——
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Indication——
Chemical Information
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CAS Number4199-88-6
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Formula Weight225.2
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Molecular FormulaC12H7N3O2
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Purity>98% (HPLC)
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Solubility——
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SMILESO=[N+]([O-])c1cc2cccnc2c2ncccc12
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Chemical Name5-Nitro-110-phenanthroline
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Liu H Robbins M Mehrotra A et al. The Impact of Using Mid-level Providers in Face-to-Face Primary Care on Health Care Utilization[J]. Medical care 2016 55(1).
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