SD 169( —— )

Catalog No. M20928 CAS No. 1670-87-7

SD 169 is a selective and ATP competitive the MAP kinases p38α and p38β inhibitor.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
1 mL x 10 mM in DMSO	28	In Stock
50MG	32	In Stock
100MG	47	In Stock
200MG	70	In Stock
500MG	Get Quote	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

SD 169
Note

Research use only, not for human use.
Brief Description

SD 169 is a selective and ATP competitive the MAP kinases p38α and p38β inhibitor.
Description

SD 169 is a selective and ATP competitive the MAP kinases p38α and p38β inhibitor.
In Vitro

SD-169 significantly reduces p38 and HSP60 expression in T cells of the pancreatic beta islets.SD-169 demonstrates 38-fold potency against p38α MAP kinase (IC50=3.2 nM) than p38β MAP kinase (IC50=122 nM).
In Vivo

——
Synonyms

——
Pathway

MAPK/ERK Signaling
Target

p38 MAPK
Recptor

p38
Research Area

——
Indication

——

Chemical Information

CAS Number

1670-87-7
Formula Weight

160.17
Molecular Formula

C9H8N2O
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 100 mg/mL (624.30 mM)
SMILES

NC(=O)c1ccc2[nH]ccc2c1
Chemical Name

1H-Indole-5-carboxamide

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Myers R R Sekiguchi Y Kikuchi S et al. Inhibition of p38 MAP kinase activity enhances axonal regeneration[J]. Experimental Neurology 2003 184(2):0-614.

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