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2-cyano-Pyrimidine
CAS No. 14080-23-0
2-cyano-Pyrimidine( —— )
Catalog No. M20858 CAS No. 14080-23-0
2-cyano-Pyrimidine is inhibitor of cathepsin K(IC50 : 170 nM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 28 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | 27 | In Stock |
|
Biological Information
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Product Name2-cyano-Pyrimidine
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NoteResearch use only, not for human use.
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Brief Description2-cyano-Pyrimidine is inhibitor of cathepsin K(IC50 : 170 nM).
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Description2-cyano-Pyrimidine is inhibitor of cathepsin K(IC50 : 170 nM).
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In Vitro2-Cyanopyrimidine is a 2-cyano-4-cyclohexylamino-pyrimidine derivative. Cathepsin K is a lysosomal cysteine protease.
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In Vivo——
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Synonyms——
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PathwayProteasome/Ubiquitin
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TargetCysteine Protease
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RecptorCathepsin K
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Research Area——
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Indication——
Chemical Information
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CAS Number14080-23-0
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Formula Weight105.1
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Molecular FormulaC5H3N3
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Purity>98% (HPLC)
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SolubilityDMSO:1mg/mL(9.51mM)
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SMILESN#Cc1ncccn1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Rankovic Z Cai J Kerr J et al. Optimisation of 2-cyano-pyrimidine inhibitors of cathepsin K: Improving selectivity over hERG[J]. Bioorganic and Medicinal Chemistry Letters 2010 20(21):6237-6241.
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