Fucoidan

CAS No. 9072-19-9

Fucoidan( —— )

Catalog No. M20853 CAS No. 9072-19-9

Fucoidan is found in various species of brown seaweed and algaewith anticancer antiviral neuroprotective immune-modulating.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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100MG 41 In Stock
500MG 125 In Stock
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Biological Information

  • Product Name
    Fucoidan
  • Note
    Research use only, not for human use.
  • Brief Description
    Fucoidan is found in various species of brown seaweed and algaewith anticancer antiviral neuroprotective immune-modulating.
  • Description
    Fucoidan is found in various species of brown seaweed and algaewith anticancer antiviral neuroprotective immune-modulating.
  • In Vitro
    Fucoidan is a biologically active polysaccharide found in great abundance in brown marine algae. Fucoidan extracted from A. nodosum is a more potent inhibitor of α-glucosidase, with an IC50 ranging from 0.013 to 0.047 mg/mL, than the inhibition by Fucoidan extracted from F. vesiculosus (IC50=0.049 mg/mL). Fucoidan extracted from F. vesiculosus does not inhibit α-amylase activity, while Fucoidan from A. nodosum decreases α-amylase activity by 7-100% at 5 mg/mL depending upon the algae harvest period. Fucoidan from A. nodosum inhibits α-amylase with an IC50 of 0.12-4.64 mg/mL.Fucoidan is a fucose-rich sulfated polysaccharide typically found in the cell wall of marine algae but also recently isolated from terrestrial sources. Fucoidan exhibits an attractive therapeutic potential against a wide array of metabolic diseases associated with oxidative stress.
  • In Vivo
    Fucoidan (single injection of 25 mg/kg/body) does not inhibit tumor cell proliferation, while three-time injections of 10 mg/kg/body weight significantly reduces tumor growth and metastasis. Animal Model:Mice Dosage:10-400 mg/kg Administration:Intraperitoneal injection; followed by total-body irradiation Result:The mice injected with 100 mg/kg showed the best survival rate at 30 days post-irradiation.
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    9072-19-9
  • Formula Weight
    242.25
  • Molecular Formula
    C7H14O7S
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?H2O : 10 mg/mL
  • SMILES
    ——
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Wang Z J Xu W Liang J W et al. EFFECT OF FUCOIDAN ON B16 MURINE MELANOMA CELL MELANIN FORMATION AND APOPTOSI[J]. African Journal of Traditional Complementary and Alternative Medicines 2017 14(4):149-155.
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