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γ-L-Glutamyl-L-alanine

CAS No. 5875-41-2

γ-L-Glutamyl-L-alanine( —— )

Catalog No. M20846 CAS No. 5875-41-2

γ-L-Glutamyl-L-alanine composed of gamma-glutamate and alanine is the substrate of CRF21 (gamma-Glutamylcyclotransferase GGCT).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    γ-L-Glutamyl-L-alanine
  • Note
    Research use only, not for human use.
  • Brief Description
    γ-L-Glutamyl-L-alanine composed of gamma-glutamate and alanine is the substrate of CRF21 (gamma-Glutamylcyclotransferase GGCT).
  • Description
    γ-L-Glutamyl-L-alanine composed of gamma-glutamate and alanine is the substrate of CRF21 (gamma-Glutamylcyclotransferase GGCT).
  • In Vitro
    γ-L-Glutamyl-L-alanine (γ-Glu-Ala) shows the potency for Ca2+i mobilization in CaR (calcium-sensing receptor)-expressing HEK-293 cells, with an EC50 of 4.8 μM.γ-L-Glutamyl-L-alanine shows the potency for Ca2+i mobilization in human parathyroid cells with an EC50 of 13.9 μM.γ-L-Glutamyl-L-alanine (20 μM) suppress PTH secretion from normal human parathyroid cells.γ-L-Glutamyl-L-alanine is a substrate for glutaminase B.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    5875-41-2
  • Formula Weight
    218.21
  • Molecular Formula
    C8H14N2O5
  • Purity
    >98% (HPLC)
  • Solubility
    H2O:50 mg/mL (229.14 mM)
  • SMILES
    CC(NC(=O)CCC(N)C(=O)O)C(=O)O
  • Chemical Name
    (2S)-2-Amino-5-[[(1S)-1-carboxyethyl]amino]-5-oxopentanoic acid

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Ovchinnikova O G Arbatsky N P Chizhov A O et al. Structure of a polysaccharide from Providencia rustigianii O11 containing a novel amide of 2-acetamido-2-deoxygalacturonic acid with l-glutamyl-l-alanine[J]. Carbohydr Res 2012 349(none):95-102.
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