γ-L-Glutamyl-L-alanine

CAS No. 5875-41-2

γ-L-Glutamyl-L-alanine( —— )

Catalog No. M20846 CAS No. 5875-41-2

γ-L-Glutamyl-L-alanine composed of gamma-glutamate and alanine is the substrate of CRF21 (gamma-Glutamylcyclotransferase GGCT).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
25MG 29 In Stock
50MG 37 In Stock
100MG 60 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    γ-L-Glutamyl-L-alanine
  • Note
    Research use only, not for human use.
  • Brief Description
    γ-L-Glutamyl-L-alanine composed of gamma-glutamate and alanine is the substrate of CRF21 (gamma-Glutamylcyclotransferase GGCT).
  • Description
    γ-L-Glutamyl-L-alanine composed of gamma-glutamate and alanine is the substrate of CRF21 (gamma-Glutamylcyclotransferase GGCT).
  • In Vitro
    γ-L-Glutamyl-L-alanine (γ-Glu-Ala) shows the potency for Ca2+i mobilization in CaR (calcium-sensing receptor)-expressing HEK-293 cells, with an EC50 of 4.8 μM.γ-L-Glutamyl-L-alanine shows the potency for Ca2+i mobilization in human parathyroid cells with an EC50 of 13.9 μM.γ-L-Glutamyl-L-alanine (20 μM) suppress PTH secretion from normal human parathyroid cells.γ-L-Glutamyl-L-alanine is a substrate for glutaminase B.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    5875-41-2
  • Formula Weight
    218.21
  • Molecular Formula
    C8H14N2O5
  • Purity
    >98% (HPLC)
  • Solubility
    H2O:50 mg/mL (229.14 mM)
  • SMILES
    CC(NC(=O)CCC(N)C(=O)O)C(=O)O
  • Chemical Name
    (2S)-2-Amino-5-[[(1S)-1-carboxyethyl]amino]-5-oxopentanoic acid

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Ovchinnikova O G Arbatsky N P Chizhov A O et al. Structure of a polysaccharide from Providencia rustigianii O11 containing a novel amide of 2-acetamido-2-deoxygalacturonic acid with l-glutamyl-l-alanine[J]. Carbohydr Res 2012 349(none):95-102.
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