γ-L-Glutamyl-L-alanine
CAS No. 5875-41-2
γ-L-Glutamyl-L-alanine( —— )
Catalog No. M20846 CAS No. 5875-41-2
γ-L-Glutamyl-L-alanine composed of gamma-glutamate and alanine is the substrate of CRF21 (gamma-Glutamylcyclotransferase GGCT).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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| 50MG | 37 | In Stock |
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| 100MG | 60 | In Stock |
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Biological Information
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Product Nameγ-L-Glutamyl-L-alanine
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NoteResearch use only, not for human use.
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Brief Descriptionγ-L-Glutamyl-L-alanine composed of gamma-glutamate and alanine is the substrate of CRF21 (gamma-Glutamylcyclotransferase GGCT).
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Descriptionγ-L-Glutamyl-L-alanine composed of gamma-glutamate and alanine is the substrate of CRF21 (gamma-Glutamylcyclotransferase GGCT).
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In Vitroγ-L-Glutamyl-L-alanine (γ-Glu-Ala) shows the potency for Ca2+i mobilization in CaR (calcium-sensing receptor)-expressing HEK-293 cells, with an EC50 of 4.8 μM.γ-L-Glutamyl-L-alanine shows the potency for Ca2+i mobilization in human parathyroid cells with an EC50 of 13.9 μM.γ-L-Glutamyl-L-alanine (20 μM) suppress PTH secretion from normal human parathyroid cells.γ-L-Glutamyl-L-alanine is a substrate for glutaminase B.
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research Area——
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Indication——
Chemical Information
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CAS Number5875-41-2
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Formula Weight218.21
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Molecular FormulaC8H14N2O5
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Purity>98% (HPLC)
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SolubilityH2O:50 mg/mL (229.14 mM)
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SMILESCC(NC(=O)CCC(N)C(=O)O)C(=O)O
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Chemical Name(2S)-2-Amino-5-[[(1S)-1-carboxyethyl]amino]-5-oxopentanoic acid
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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Rnase (90-105)
Rnase (90-105)
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Betanin
Betanin is a natural red-violet food dye obtained from beets.
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γ-2-MSH (41-58), ami...
Melanocortin (MC) 3-MSH (Melanocyte-Stimulating Hormone) is believed to signal through the MC 3 receptor. It induces a sustained increase in intracellular free calcium levels ([Ca2+]i) in a subpopulation of pituitary cells. Most of the cells responding to 3-MSH express more than one pituitary hormone mRNA. The effect of 3-MSH is blocked by SHU9119, a MC3R and MC4R antagonist, in only 50% of the responsive cells, suggesting that in half of these cells the mediating receptor is not the MC3R. Low picomolar doses of 3-MSH increase [Ca2+]i in the growth hormone (GH)- and prolactin (PRL)-secreting GH3 cell line.
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