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Budipine

CAS No. 57982-78-2

Budipine( —— )

Catalog No. M20845 CAS No. 57982-78-2

Budipine is a low affinity N-methyl-D-aspartate receptor antagonistis an antiparkinsonian agent.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 37 In Stock
5MG 33 In Stock
10MG 55 In Stock
25MG 111 In Stock
50MG 207 In Stock
100MG 306 In Stock
200MG 442 In Stock
500MG Get Quote In Stock
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Biological Information

  • Product Name
    Budipine
  • Note
    Research use only, not for human use.
  • Brief Description
    Budipine is a low affinity N-methyl-D-aspartate receptor antagonistis an antiparkinsonian agent.
  • Description
    Budipine is a low affinity N-methyl-D-aspartate receptor antagonistis an antiparkinsonian agent.
  • In Vitro
    ——
  • In Vivo
    Budipine (s.c., 30 μg/24 h, 11 days) is a substrate of P-glycoprotein (P-gp) and is actively transported out of the brain through the blood–brain barrier back into the blood plasma. Animal Model:Male abcblab(-/-) mice Male abcblab(-/-) mice (n=8, weight 29.0 g) and FVB/N wild-type mice (n =8, weight 28.0 g).Dosage:30 μg(Budipine is dissolved in 0.9% sodium chloride and 0.5% ethanol).Administration:subcutaneous injections, continuously delivered 30 μg over 24 h, 11 days Result:Increased the cerebrum concentration for 3.1 times high in knock-out mice after an 11-day continuous administration.Showed no significant differences in plasma, spleen, kidney and liver.
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    N-methyl-D-aspartate
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    57982-78-2
  • Formula Weight
    293.45
  • Molecular Formula
    C21H27N
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 25 mg/mL (85.19 mM)
  • SMILES
    CC(C)(C)N1CCC(c2ccccc2)(c2ccccc2)CC1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Eltze M.Multiple mechanisms of action: the pharmacological profile of budipine.J Neural Transm Suppl. 1999;56:83-105.
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