Cart
sales@molnova.com
Home - Products - Membrane Transporter/Ion Channel - Sodium Channel - Ralfinamide mesylate

Ralfinamide mesylate

CAS No. 202825-45-4

Ralfinamide mesylate( FCE-26742A (mesylate) )

Catalog No. M20790 CAS No. 202825-45-4

Ralfinamide mesylate is an orally available Na+ channel blocker.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 181 In Stock
5MG 115 In Stock
10MG 180 In Stock
25MG 296 In Stock
50MG 384 In Stock
100MG 542 In Stock
200MG 728 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    Ralfinamide mesylate
  • Note
    Research use only, not for human use.
  • Brief Description
    Ralfinamide mesylate is an orally available Na+ channel blocker.
  • Description
    Ralfinamide mesylate is an orally available Na+ channel blocker.
  • In Vitro
    ——
  • In Vivo
    Ralfinamide (30 mg/kg, 60 mg/kg; p.o.; twice daily; 42 days) treated with Ralfinamide (80 mg/kg; p.o.; twice daily; 7 days) preoperatively suppresses neuropathic pain. Animal Model:81 adult male Sprague–Dawley male rats (260–460 g) Dosage:80 mg/kg (7 days preoperatively), 30 mg/kg, 60 mg/kg (postoperative)Administration:Oral gavage; twice daily; until postoperative day 42 Result:Suppressed neuropathic pain.
  • Synonyms
    FCE-26742A (mesylate)
  • Pathway
    Membrane Transporter/Ion Channel
  • Target
    Sodium Channel
  • Recptor
    Sodium Channel
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    202825-45-4
  • Formula Weight
    398.45
  • Molecular Formula
    C18H23FN2O5S?
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    CC(NCc1ccc(OCc2ccccc2F)cc1)C(N)=O.CS(=O)(=O)O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Liang X Yu G Su R . Effects of ralfinamide in models of nerve injury and chemotherapy-induced neuropathic pain[J]. European journal of pharmacology 2018 823:27-34.
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • Articaine HCl

    Articaine is a dental local anesthetic which contains an additional ester group that is metabolized by estearases in blood and tissue.

  • APETx2

    Acid-sensing ion channel 3 (ASIC3) channel blocker (IC50 values are 63 and 175 nM for homomeric rat and human ASIC3 channels). Also inhibits NaV1.8 and NaV1.2 channels (IC50 values are 55 and 114 nM respectively). Demonstrates analgesic properties against acid-induced and inflammatory pain.

  • PF-05150122

    PF-05150122 is a potent, state-dependent, subtype selective Nav1.7 inhibitor with IC50 of 21 nM.

Sign In Join Free