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Dihexa

CAS No. 1401708-83-5

Dihexa( PNB-0408 | N-hexanoic-Try-Ile-(6)-amino hexanoic amide | Hexanoyl-Tyr-Ile-Ahx-NH2 )

Catalog No. M20716 CAS No. 1401708-83-5

Dihexa is an activator of the hepatocyte growth factor/c-Met (HGF/c-Met) systemit binds to HGF (Kd = 65 pM)and an analog of the peptide angiotensin IV.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Dihexa
  • Note
    Research use only, not for human use.
  • Brief Description
    Dihexa is an activator of the hepatocyte growth factor/c-Met (HGF/c-Met) systemit binds to HGF (Kd = 65 pM)and an analog of the peptide angiotensin IV.
  • Description
    Dihexa is an activator of the hepatocyte growth factor/c-Met (HGF/c-Met) systemit binds to HGF (Kd = 65 pM)and an analog of the peptide angiotensin IV.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    PNB-0408 | N-hexanoic-Try-Ile-(6)-amino hexanoic amide | Hexanoyl-Tyr-Ile-Ahx-NH2
  • Pathway
    Angiogenesis
  • Target
    c-Met/HGFR
  • Recptor
    HGF
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1401708-83-5
  • Formula Weight
    504.66
  • Molecular Formula
    C27H44N4O5
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:30 mg/mL (59.45 mM)
  • SMILES
    CCCCCC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)NCCCCCC(N)=O
  • Chemical Name
    6-[(2S3S)-2-[(2S)-2-hexanamido-3-(4-hydroxyphenyl)propanamido]-3-methylpentanamido]hexanamide

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Mccoy A T Benoist C C Wright J W et al. Evaluation of Metabolically Stabilized Angiotensin IV Analogs as Procognitive/Antidementia Agents[J]. Journal of Pharmacology and Experimental Therapeutics 2013 344(1):141-154.
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