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CNQX

CAS No. 115066-14-3

CNQX( FG9065 )

Catalog No. M20706 CAS No. 115066-14-3

CNQX is a competitive non-NMDA glutamate receptor antagonist (IC50s = 0.3 and 1.5 μM for AMPA and kainate receptors respectively).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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5MG 37 In Stock
10MG 51 In Stock
25MG 112 In Stock
50MG 177 In Stock
100MG 284 In Stock
200MG 428 In Stock
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Biological Information

  • Product Name
    CNQX
  • Note
    Research use only, not for human use.
  • Brief Description
    CNQX is a competitive non-NMDA glutamate receptor antagonist (IC50s = 0.3 and 1.5 μM for AMPA and kainate receptors respectively).
  • Description
    CNQX is a competitive non-NMDA glutamate receptor antagonist (IC50s = 0.3 and 1.5 μM for AMPA and kainate receptors respectively).
  • In Vitro
    ——
  • In Vivo
    Animal Model:Male Wistar rats weighing 180-200 g Dosage:0.75, 1.5, and 3 mg/kg Administration:IP; 20 min before testing Result:Decreased the number of cocaine (IV; 0.25 mg/infusion) responses in a dose-dependent manner during the first 15-min cocaine-free interval.
  • Synonyms
    FG9065
  • Pathway
    Neuroscience
  • Target
    GluR
  • Recptor
    AMPA
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    115066-14-3
  • Formula Weight
    232.15
  • Molecular Formula
    C9H4N4O4
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:30 mg/mL (129.23 mM)
  • SMILES
    [O-][N+](=O)c1cc2[nH]c(=O)c(=O)[nH]c2cc1C#N
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Blake J F Brown M W Collingridge G L . CNQX blocks acidic amino acid induced depolarizations and synaptic components mediated by non-NMDA receptors in rat hippocampal slices[J]. Neuroscience letters 1988 89(2):182-186.
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