Cephalosporin C zinc salt( —— )

Catalog No. M20689 CAS No. 59143-60-1

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

Cephalosporin C zinc salt
Note

Research use only, not for human use.
Brief Description

Cephalosporin C zinc salt was a potent inhibitor of SAMHD1 (IC50 : 1.1 ± 0.1 μM) and this inhibition was largely attributable to the presence of zinc.
Description

Cephalosporin C zinc salt was a potent inhibitor of SAMHD1 (IC50 : 1.1 ± 0.1 μM) and this inhibition was largely attributable to the presence of zinc.
In Vitro

Cephalosporin C zinc salt is a potent inhibitor of SAMHD1 with an IC50 of 1.1 ± 0.1 μM, 200-fold more potent than Na+ salt form of Cephalosporin C (ICC50CC-Na = 213 ± 30 μM).
In Vivo

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Synonyms

——
Pathway

Others
Target

Other Targets
Recptor

SAMHD1?
Research Area

——
Indication

——

CAS Number

59143-60-1
Formula Weight

478.78
Molecular Formula

C16H19N3O8SZn
Purity

>98% (HPLC)
Solubility

DMSO:6 mg/mL (12.53 mM)
SMILES

[Zn++].[H][C@@]12SCC(CC(C)=O)=C(N1C(=O)[C@H]2NC(=O)CCC[C@@H](N)C([O-])=O)C([O-])=O
Chemical Name

——

1.Seamon K J Stivers J T . A high-throughput enzyme-coupled assay for SAMHD1 dNTPase[J]. Journal of Biomolecular Screening 2015 20(6).

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