Sultopride hydrochloride( LIN-1418 hydrochloride )

Catalog No. M20670 CAS No. 23694-17-9

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Product Name

Sultopride hydrochloride
Note

Research use only, not for human use.
Brief Description

Sultopride Hydrochloride is a selective dopamine D2 and D3 receptor antagonist.
Description

Sultopride Hydrochloride is a selective dopamine D2 and D3 receptor antagonist.
In Vitro

——
In Vivo

Sultopride hydrochloride (LIN-1418 hydrochloride) is a selective antagonist of dopamine D2 receptor. DOPAC and HVA levels in the striatum, the nucleus accumbens and the medial prefrontal cortex are higher in the rats treated with Sultopride hydrochloride and sulpiride than those of the controls. In the striatum, DOPAC and HVA levels are higher in the Sultopride hydrochloride-treated rats than the sulpiride-treated rats (p<0.05). In the nucleus accumbens, DOPAC levels are higher in the Sultopride hydrochloride-treated rats than sulpiride treated rats (p<0.05). In the Sultopride hydrochloride-treated rats, DOPAC and HVA levels are higher in the striatum or in the nucleus accumbens than in the medial prefrontal cortex (p<0.05).
Synonyms

LIN-1418 hydrochloride
Pathway

GPCR/G Protein
Target

Dopamine Receptor
Recptor

Dopamine
Research Area

——
Indication

——

CAS Number

23694-17-9
Formula Weight

390.93
Molecular Formula

C17H27ClN2O4S
Purity

>98% (HPLC)
Solubility

DMSO:50 mg/mL (127.90 mM)
SMILES

Cl.CCN1CCCC1CNC(=O)c1cc(ccc1OC)S(=O)(=O)CC
Chemical Name

N-((1-Ethylpyrrolidin-2-yl)methyl)-5-(ethylsulfonyl)-2-methoxybenzamide hydrochloride

1.Differences in effects of sultopride and sulpiride on dopamine turnover in rat brain.

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