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CU-CPT-9a

CAS No. 2165340-32-7

CU-CPT-9a( —— )

Catalog No. M20662 CAS No. 2165340-32-7

CU-CPT-9a is a potent TLR8 inhibitor (IC50 : 0.5 nM) that suppresses TLR8-mediated proinflammatory signaling in various cell lines.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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5MG 72 In Stock
10MG 115 In Stock
25MG 224 In Stock
50MG 410 In Stock
100MG 605 In Stock
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Biological Information

  • Product Name
    CU-CPT-9a
  • Note
    Research use only, not for human use.
  • Brief Description
    CU-CPT-9a is a potent TLR8 inhibitor (IC50 : 0.5 nM) that suppresses TLR8-mediated proinflammatory signaling in various cell lines.
  • Description
    CU-CPT-9a is a potent TLR8 inhibitor (IC50 : 0.5 nM) that suppresses TLR8-mediated proinflammatory signaling in various cell lines and human primary cells.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Immunology/Inflammation
  • Target
    TLR
  • Recptor
    TLR8
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2165340-32-7
  • Formula Weight
    265.31
  • Molecular Formula
    C17H15NO2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:150 mg/mL (565.38 mM)
  • SMILES
    COc1ccc2c(ccnc2c1)-c1ccc(O)c(C)c1
  • Chemical Name
    2-Methyl-4-(7-methoxy-4-quinolinyl)phenol

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Zhang S Hu Z Tanji H et al. Small-molecule inhibition of TLR8 through stabilization of its resting state[J]. Nature Chemical Biology 2017 14(1):58-64.
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