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Maropitant
CAS No. 147116-67-4
Maropitant( —— )
Catalog No. M20648 CAS No. 147116-67-4
Maropitant is a selective neurokinin (NK1) receptor antagonist.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 39 | In Stock |
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| 5MG | 65 | In Stock |
|
| 10MG | 110 | In Stock |
|
| 25MG | 177 | In Stock |
|
| 50MG | 335 | In Stock |
|
| 100MG | 500 | In Stock |
|
| 500MG | 1098 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameMaropitant
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NoteResearch use only, not for human use.
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Brief DescriptionMaropitant is a selective neurokinin (NK1) receptor antagonist.
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DescriptionMaropitant is a selective neurokinin (NK1) receptor antagonist.
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In Vitro——
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In VivoTreatment with 1 mg/kg Maropitant citrate, significantly reduces the size of ulcerative dermatitis (UD) lesions in mice. Intravenous Maropitant decreases MAC by 16%. In contrast, epidural administration of either saline or Maropitant does not change the MAC (2.17% and 1.92 %, respectively).
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Synonyms——
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PathwayGPCR/G Protein
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TargetNeurokinin Receptor
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RecptorNK1
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Research Area——
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Indication——
Chemical Information
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CAS Number147116-67-4
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Formula Weight468.67
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Molecular FormulaC32H40N2O
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Purity>98% (HPLC)
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SolubilityDMSO:33.33 mg/mL (71.12 mM)
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SMILESCOc1ccc(cc1CN[C@H]1C2CCN(CC2)[C@H]1C(c1ccccc1)c1ccccc1)C(C)(C)C
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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Substance P (1-9)
Substance P (1-9) is nonapeptide, which decreases the inactivation of substance P by the guinea-pig ileum and urinary bladder. Subtance P is responsible for a number of excitatory effects on both central and peripheral neurons.
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Hemokinin 1 (human)
Endogenous substance P homolog that is a selective agonist at the tachykinin NK1 receptor (IC50 values are 1.8, 370 and 480 nM for NK1, NK3 and NK2 receptors respectively). Has proliferative and antiapoptotic actions on B-cells in vitro and is antihypertensive in vivo.
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[Sar9,Met(O2)11]-Sub...
Sar9, Met (O2)11-Substance P is a neurokinin-1 receptor agonist. It is an analog of the naturally occurring human neuropeptide Substance P, which can be found throughout the body, including in the airways of humans and many other species.
