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3-Chloro-L-alanine

CAS No. 2731-73-9

3-Chloro-L-alanine( β-Chloro-L-alanine | L-β-Chloroalanine )

Catalog No. M20568 CAS No. 2731-73-9

3-Chloro-L-alanine is a bacteriostatic amino acid analog which inhibits a number of enzymes including threonine deaminase and alanine racemase.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    3-Chloro-L-alanine
  • Note
    Research use only, not for human use.
  • Brief Description
    3-Chloro-L-alanine is a bacteriostatic amino acid analog which inhibits a number of enzymes including threonine deaminase and alanine racemase.
  • Description
    3-Chloro-L-alanine is a bacteriostatic amino acid analog which inhibits a number of enzymes including threonine deaminase and alanine racemase.
  • In Vitro
    β-Chloro-L-alanine can inhibit threonine deaminase, the branched-chain amino acid transaminase (transaminase B), L-aspartate-pdecarboxylase, alanine racemase and probably O-acetylserine sulfhydrylase. β-Chloro-L-alanine reversibly inhibits the Escherichia coli K-12 alanine-valine transaminase, transaminase C. This inhibition, along with the inhibition of transaminase B, account for the isoleucine-plus-valine requirement of Escherichia coli in the presence of β-Chloro-L-alanine. Salmonella typhimurium LT2 will grow in the presence of BCA if isoleucine and valine are added to the medium and presume that the growth requirement is due to the inhibition of transaminase B.
  • In Vivo
    ——
  • Synonyms
    β-Chloro-L-alanine | L-β-Chloroalanine
  • Pathway
    GPCR/G Protein
  • Target
    Antibacterial
  • Recptor
    Bacterial
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2731-73-9
  • Formula Weight
    123.54
  • Molecular Formula
    C3H6ClNO2
  • Purity
    >98% (HPLC)
  • Solubility
    H2O:30 mg/mL (242.84 mM)
  • SMILES
    N[C@@H](CCl)C(O)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Whalen W A Wang M D Berg C M . beta-Chloro-L-alanine inhibition of the Escherichia coli alanine-valine transaminase.[J]. Journal of Bacteriology 1985 164(3):1350-2.
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