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34-Dihydro-7-hydroxy-2(1H)-quinolinone

CAS No. 22246-18-0

34-Dihydro-7-hydroxy-2(1H)-quinolinone( 7-Hydroxy-34-dihydro-2(1H)-quinolinone )

Catalog No. M20560 CAS No. 22246-18-0

34-Dihydro-7-hydroxy-2(1H)-quinolinone (7- Hydroxy- 3 4- dihydro- 2(1H) - quinolinone) is a weak MAO-A inhibitor(with an IC50 of 183 μM) .

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 28 In Stock
100MG Get Quote In Stock
200MG Get Quote In Stock
500MG 27 In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    34-Dihydro-7-hydroxy-2(1H)-quinolinone
  • Note
    Research use only, not for human use.
  • Brief Description
    34-Dihydro-7-hydroxy-2(1H)-quinolinone (7- Hydroxy- 3 4- dihydro- 2(1H) - quinolinone) is a weak MAO-A inhibitor(with an IC50 of 183 μM) .
  • Description
    34-Dihydro-7-hydroxy-2(1H)-quinolinone (7- Hydroxy- 3 4- dihydro- 2(1H) - quinolinone) is a weak MAO-A inhibitor(with an IC50 of 183 μM) .
  • In Vitro
    7-?Hydroxy-?3,?4-?dihydro-?2(1H)?-?quinolinone is a weak MAO-A inhibitor, with an IC50 of 183 μM, and has no effect on MAO-B.
  • In Vivo
    ——
  • Synonyms
    7-Hydroxy-34-dihydro-2(1H)-quinolinone
  • Pathway
    Metabolic Enzyme/Protease
  • Target
    MAO
  • Recptor
    MAO-A
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    22246-18-0
  • Formula Weight
    163.17
  • Molecular Formula
    C9H9NO2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:32 mg/mL (196.11 mM)
  • SMILES
    Oc1ccc2CCC(=O)Nc2c1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Meiring L Petzer J P Petzer Anél. Inhibition of monoamine oxidase by 34-dihydro-2(1H)-quinolinone derivatives[J]. Bioorganic & Medicinal Chemistry Letters 2013 23(20):5498-5502.
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