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4-Butylresorcinol
CAS No. 18979-61-8
4-Butylresorcinol( Butylresorcinol )
Catalog No. M20556 CAS No. 18979-61-8
4-Butylresorcinol is a potent inhibitor of tyrosinase(IC50 : 11.27 μM) and is used in cosmetics as a depigmenting agent.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 37 | In Stock |
|
| 100MG | 32 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product Name4-Butylresorcinol
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NoteResearch use only, not for human use.
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Brief Description4-Butylresorcinol is a potent inhibitor of tyrosinase(IC50 : 11.27 μM) and is used in cosmetics as a depigmenting agent.
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Description4-Butylresorcinol is a potent inhibitor of tyrosinase(IC50 : 11.27 μM) and is used in cosmetics as a depigmenting agent.
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In VitroIt shows that 4-Butylresorcinol (4-n-butylresorcinol) significantly inhibits melanin synthesis in a concentration-dependent manner. In addition, it is also found to inhibit the activity of tyrosinase, the rate-limiting melanogenic enzyme. 4-Butylresorcinol does not induce ERK, Akt activation, or MITF degradation, and has no effect on cAMP response element binding protein (CREB) phosphorylation, which stimulates MITF expression.4-Butylresorcinol strongly reduces tyrosinase activity in a cell-free system. Moreover, 4-Butylresorcinol shows an additive effect in combination with hinokitiol, which reduces MITF expression.
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In Vivo——
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SynonymsButylresorcinol
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PathwayProteasome/Ubiquitin
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TargetTyrosinase
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RecptorTyrosinase
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Research Area——
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Indication——
Chemical Information
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CAS Number18979-61-8
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Formula Weight166.22
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Molecular FormulaC10H14O2
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Purity>98% (HPLC)
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SolubilityDMSO:150 mg/mL (902.42 mM)
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SMILESCCCCc1ccc(O)cc1O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Kim D S Kim S Y Park S H et al. Inhibitory Effects of 4-n-Butylresorcinol on Tyrosinase Activity and Melanin Synthesis[J]. Biological & Pharmaceutical Bulletin 2005 28(12):2216-2219.
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