Cart
sales@molnova.com
Nortadalafil
CAS No. 171596-36-4
Nortadalafil( Demethyl Tadalafil )
Catalog No. M20552 CAS No. 171596-36-4
Nortadalafil is demethyl Tadalafil which is a PDE5 inhibitor treating erectile dysfunction (ED) ; and under the name Adcirca for the treatment of pulmonary arterial hypertensio.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 75 | In Stock |
|
| 2MG | 42 | In Stock |
|
| 5MG | 68 | In Stock |
|
| 10MG | 107 | In Stock |
|
| 25MG | 202 | In Stock |
|
| 50MG | 346 | In Stock |
|
| 100MG | 555 | In Stock |
|
| 200MG | 788 | In Stock |
|
| 500MG | 1172 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameNortadalafil
-
NoteResearch use only, not for human use.
-
Brief DescriptionNortadalafil is demethyl Tadalafil which is a PDE5 inhibitor treating erectile dysfunction (ED) ; and under the name Adcirca for the treatment of pulmonary arterial hypertensio.
-
DescriptionNortadalafil is demethyl Tadalafil which is a PDE5 inhibitor treating erectile dysfunction (ED) ; and under the name Adcirca for the treatment of pulmonary arterial hypertensio.
-
In Vitro——
-
In Vivo——
-
SynonymsDemethyl Tadalafil
-
PathwayAngiogenesis
-
TargetPDE
-
RecptorPDE5
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number171596-36-4
-
Formula Weight375.38
-
Molecular FormulaC21H16N3O4
-
Purity>98% (HPLC)
-
SolubilityDMSO:50 mg/mL (133.20 mM)
-
SMILESO=C1CNC(=O)[C@H]2Cc3c([nH]c4ccccc34)[C@H](N12)c1ccc2OCOc2c1
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Takahiro R Nakamura S Kohno H et al. Contribution of CYP3A Isoforms to Dealkylation of PDE5 Inhibitors: A Comparison between Sildenafil N-Demethylation and Tadalafil Demethylenation[J]. Biological & Pharmaceutical Bulletin 2015 38(1):58-65.
molnova catalog
related products
-
uk-50001
uk-50001 is a phosphodiesterase (PDE) 4 inhibitor that can be used for many diseases, especially inflammation, allergies, respiratory diseases, disorders and conditions and wounds.
-
PDE IV-IN-1
PDE IV-IN-1 is a potent phosphodiesterase 4 (PDE4) inhibitor with anti-inflammatory activity for the treatment of asthma, chronic obstructive pulmonary disease and other inflammatory diseases, and is a potential compound for the study of depression.
-
MR-L2
MR-L2 is a reversible and noncompetitive allosteric activator of long-isoform phosphodiesterase-4 (PDE4).
