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Nortadalafil
CAS No. 171596-36-4
Nortadalafil( Demethyl Tadalafil )
Catalog No. M20552 CAS No. 171596-36-4
Nortadalafil is demethyl Tadalafil which is a PDE5 inhibitor treating erectile dysfunction (ED) ; and under the name Adcirca for the treatment of pulmonary arterial hypertensio.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 75 | In Stock |
|
| 2MG | 42 | In Stock |
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| 5MG | 68 | In Stock |
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| 10MG | 107 | In Stock |
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| 25MG | 202 | In Stock |
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| 50MG | 346 | In Stock |
|
| 100MG | 555 | In Stock |
|
| 200MG | 788 | In Stock |
|
| 500MG | 1172 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameNortadalafil
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NoteResearch use only, not for human use.
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Brief DescriptionNortadalafil is demethyl Tadalafil which is a PDE5 inhibitor treating erectile dysfunction (ED) ; and under the name Adcirca for the treatment of pulmonary arterial hypertensio.
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DescriptionNortadalafil is demethyl Tadalafil which is a PDE5 inhibitor treating erectile dysfunction (ED) ; and under the name Adcirca for the treatment of pulmonary arterial hypertensio.
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In Vitro——
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In Vivo——
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SynonymsDemethyl Tadalafil
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PathwayAngiogenesis
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TargetPDE
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RecptorPDE5
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Research Area——
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Indication——
Chemical Information
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CAS Number171596-36-4
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Formula Weight375.38
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Molecular FormulaC21H16N3O4
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Purity>98% (HPLC)
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SolubilityDMSO:50 mg/mL (133.20 mM)
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SMILESO=C1CNC(=O)[C@H]2Cc3c([nH]c4ccccc34)[C@H](N12)c1ccc2OCOc2c1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Takahiro R Nakamura S Kohno H et al. Contribution of CYP3A Isoforms to Dealkylation of PDE5 Inhibitors: A Comparison between Sildenafil N-Demethylation and Tadalafil Demethylenation[J]. Biological & Pharmaceutical Bulletin 2015 38(1):58-65.
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