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Nortadalafil

CAS No. 171596-36-4

Nortadalafil( Demethyl Tadalafil )

Catalog No. M20552 CAS No. 171596-36-4

Nortadalafil is demethyl Tadalafil which is a PDE5 inhibitor treating erectile dysfunction (ED) ; and under the name Adcirca for the treatment of pulmonary arterial hypertensio.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 75 In Stock
2MG 42 In Stock
5MG 68 In Stock
10MG 107 In Stock
25MG 202 In Stock
50MG 346 In Stock
100MG 555 In Stock
200MG 788 In Stock
500MG 1172 In Stock
1G Get Quote In Stock
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Biological Information

  • Product Name
    Nortadalafil
  • Note
    Research use only, not for human use.
  • Brief Description
    Nortadalafil is demethyl Tadalafil which is a PDE5 inhibitor treating erectile dysfunction (ED) ; and under the name Adcirca for the treatment of pulmonary arterial hypertensio.
  • Description
    Nortadalafil is demethyl Tadalafil which is a PDE5 inhibitor treating erectile dysfunction (ED) ; and under the name Adcirca for the treatment of pulmonary arterial hypertensio.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    Demethyl Tadalafil
  • Pathway
    Angiogenesis
  • Target
    PDE
  • Recptor
    PDE5
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    171596-36-4
  • Formula Weight
    375.38
  • Molecular Formula
    C21H16N3O4
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:50 mg/mL (133.20 mM)
  • SMILES
    O=C1CNC(=O)[C@H]2Cc3c([nH]c4ccccc34)[C@H](N12)c1ccc2OCOc2c1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Takahiro R Nakamura S Kohno H et al. Contribution of CYP3A Isoforms to Dealkylation of PDE5 Inhibitors: A Comparison between Sildenafil N-Demethylation and Tadalafil Demethylenation[J]. Biological & Pharmaceutical Bulletin 2015 38(1):58-65.
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