neo-gambogic acid

CAS No. 93772-31-7

neo-gambogic acid( —— )

Catalog No. M20501 CAS No. 93772-31-7

Neogambogic acid an active ingredient in garcinia can inhibit the growth of some solid tumors and result in an anticancer effect it may be responsible for the inhibition of proliferation of human breast cancer cell line MCF-7 cells.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 93 In Stock
10MG 141 In Stock
25MG 237 In Stock
50MG 343 In Stock
100MG 510 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    neo-gambogic acid
  • Note
    Research use only, not for human use.
  • Brief Description
    Neogambogic acid an active ingredient in garcinia can inhibit the growth of some solid tumors and result in an anticancer effect it may be responsible for the inhibition of proliferation of human breast cancer cell line MCF-7 cells.
  • Description
    Neogambogic acid an active ingredient in garcinia can inhibit the growth of some solid tumors and result in an anticancer effect it may be responsible for the inhibition of proliferation of human breast cancer cell line MCF-7 cells.
  • In Vitro
    Neogambogic acid inhibits HCT-8, Bel-7402, BGC-823, A549, and A2780 cell proliferation, with an IC50 between 1.75 and 3 μM. Neogambogic acid induces A549 cells apoptosis arrested the cells to G0/G1 phase in vitro.
  • In Vivo
    Neogambogic acid arrests A549-induced tumor growth in nude mice.
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    93772-31-7
  • Formula Weight
    646.8
  • Molecular Formula
    C38H46O9?
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    C\C(C)=C\CCC1(C)CC(O)c2c(O)c3C(=O)C4=CC5CC6C(C)(C)OC(C\C=C(/C)C(O)=O)(C5=O)C46Oc3c(C\C=C(/C)C)c2O1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Wang K Tang Y Sun Met al.The mechanism of neogambogic acid-induced apoptosis in human MCF-7 cells[J].Acta Biochim Biophys Sin (Shanghai). 2011 Sep;43(9):698-702.
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