Home - Products - GPCR/G Protein - Antibacterial - Qstatin

Qstatin

CAS No. 902688-24-8

Qstatin( —— )

Catalog No. M20499 CAS No. 902688-24-8

QStatin a Selective Inhibitor of Quorum Sensing in Vibrio Species( SmcR with an EC50 of 208.9 nM).

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
1 mL x 10 mM in DMSO	29	In Stock
10MG	43	In Stock
25MG	79	In Stock
50MG	109	In Stock
100MG	155	In Stock
200MG	226	In Stock
500MG	Get Quote	In Stock
1G	Get Quote	In Stock

Get Quotation Bulk Inquiry Add to Cart

Biological Information

Product Name

Qstatin
Note

Research use only, not for human use.
Brief Description

QStatin a Selective Inhibitor of Quorum Sensing in Vibrio Species( SmcR with an EC50 of 208.9 nM).
Description

QStatin a Selective Inhibitor of Quorum Sensing in Vibrio Species( SmcR with an EC50 of 208.9 nM).
In Vitro

QStatin (0.001 μM-10 μM; 5 hours) inhibits SmcR activity measured by the RLU level for V. vulnificusWT (pBB1), reveals EC50 of 208.9 nM.QStatin (5 μM-50 μM; 16 hours) reduces the activities of SmcR-activated virulence factors (protease and elastase) in V. vulnificus in a dose dependent manner. QStatin (5 μM-50 μM; 16 hours) has no effect on the cellular levels of SmcR, indicating that QStatin does not affect the expression or stability of SmcR.
In Vivo

——
Synonyms

——
Pathway

GPCR/G Protein
Target

Antibacterial
Recptor

SmcR
Research Area

——
Indication

——

Chemical Information

CAS Number

902688-24-8
Formula Weight

293.16
Molecular Formula

C7H5BrN2O2S2
Purity

>98% (HPLC)
Solubility

DMSO:83.33 mg/mL (284.25 mM)
SMILES

Brc1ccc(s1)S(=O)(=O)n1cccn1
Chemical Name

1-(5-Bromothiophene-2-sulfonyl)-1H-pyrazole

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Kim B S Jang S Y Bang Y J et al. QStatin a Selective Inhibitor of Quorum Sensing in Vibrio Species[J]. mBio 2018 9(1).

Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog

related products

Dovitinib lactate hy...

Dovitinib (TKI258) Lactate is the Lactate of Dovitinib, which is a multitargeted RTK inhibitor, mostly for class III (FLT3/c-Kit) with IC50 of 1 nM/2 nM.
Pachybasin

Pachybasin is an anthraquinone fungal metabolite. Pachybasin shows antimicrobial activities against E. coli, B. subtilis, M. luteus, S. cerevisiae, C. albicans, A. niger, and A. flavus, with MIC values of 64.0 μg/mL, and against S. aureus and F. oxysporum with MIC values of 32.0 and 16.0 μg/mL respectively.
Praeruptorin A

Praeruptorin A has the potential to inhibit migration/fusion of preosteoclasts in vitro and bone erosion in vivo by targeting calmodulin and inhibiting the Ca(2+)/calmodulin-CaMKIV-CREB-NFATc1 and/or Ca(2+)/calmodulin-calcineurin-NFATc1 signaling axis.

Sign In Join Free